Condition (MeSH)
Cerebrospinal Fluid Leak
ClinicalTrials.gov lists 58 trials for Cerebrospinal Fluid Leak or a narrower condition beneath it.
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Trials per phase (log scale)
39 of the 58 trials are tagged with Cerebrospinal Fluid Leak itself; the rest are tagged with a narrower condition beneath it.
When did Cerebrospinal Fluid Leak trials start? (20)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 5 |
| 2025 | 3 |
| 2024 | 6 |
| 2023 | 4 |
| 2022 | 1 |
| 2021 | 4 |
| 2020 | 7 |
| 2019 | 3 |
| 2018 | 2 |
| 2017 | 2 |
Showing 10 of 20 earlier years.
No forecast is made for this condition: it averages 3.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 26 months across 33 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Cerebrospinal Fluid Leak trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 6 |
| Phase 2/3 | 1 |
| Phase 3 | 6 |
| Phase 4 | 3 |
| Not applicable | 24 |
| Observational | 18 |
How many Cerebrospinal Fluid Leak trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 10 |
| Enrolling by invitation | 1 |
| Completed | 28 |
| Terminated | 4 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Cerebrospinal Fluid Leak trials? (7)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Ethicon, Inc. | 3 |
| Medprin Regenerative Medical Technologies Co., Ltd. | 3 |
| Integra LifeSciences Corporation | 2 |
| Polyganics BV | 2 |
| Bagcilar Training and Research Hospital | 1 |
Showing 5 of 7 sponsors.
Which drugs are being tested for Cerebrospinal Fluid Leak? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Polyglycolic Acid | 1 |
Interventions as named in the registry (9)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Acetazolamide Pill | 3 |
| EVICEL Fibrin Sealant | 2 |
| TachoSil | 2 |
| PO Morphine | 1 |
| TISSEEL | 1 |
Showing 5 of 9 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Cerebrospinal Fluid Leak trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Hydrocephalus | 26 | 4 |
| Pneumonia | 23 | 4 |
| Pseudomeningocele | 19 | 4 |
| Cerebrospinal fluid leakage | 13 | 3 |
| Meningitis | 10 | 3 |
Showing 5 of 10 adverse events.
Which publications cover Cerebrospinal Fluid Leak? (50)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 50 publications.
Sub-conditions in MeSH (2)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.