Condition (MeSH)
Cockayne Syndrome
ClinicalTrials.gov lists 11 trials for Cockayne Syndrome or a narrower condition beneath it. DNage B.V. has the most among industry and government lead sponsors, with 2.
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Trials per phase
11 of the 11 trials are tagged with Cockayne Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Cockayne Syndrome trials start? (8)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1/2
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 2 |
| 2022 | 1 |
| 2020 | 1 |
| 2017 | 2 |
| 2016 | 1 |
| 2010 | 2 |
| 2009 | 1 |
| 1999 | 1 |
No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Cockayne Syndrome trials in? (3)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 1 |
| Not applicable | 2 |
| Observational | 8 |
How many Cockayne Syndrome trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 4 |
| Enrolling by invitation | 1 |
| Completed | 3 |
| Terminated | 2 |
| Unknown status | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Cockayne Syndrome trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| DNage B.V. | 2 |
| National Cancer Institute (NCI) | 1 |
Interventions as named in the registry (1)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Prodarsan | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Cockayne Syndrome? (6)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Ending a diagnostic odyssey: Moving from exome to genome to identify cockayne syndrome. | Molecular genetics & genomic medicine | 2021 | Yes |
| Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity. | Nature reviews. Genetics | 2009 | Yes |
| Evidence for defective repair of cyclobutane pyrimidine dimers with normal repair of other DNA photoproducts in a transcriptionally active gene transfected into Cockayne syndrome cells. | Mutation research | 1991 | Yes |
| MRI in Cockayne syndrome type I. | Neuroradiology | 1989 | Yes |
| Oxidative stress in developmental brain disorders. | Neuropathology : official journal of the Japanese Society of Neuropathology | 2009 | No |
Showing 5 of 6 publications.
Prevalence (24)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Cockayne syndrome | Prevalence at birth | 1-9 / 1 000 000 | United Kingdom | GB | Unspecified |
| Cockayne syndrome | Prevalence at birth | 1-9 / 1 000 000 | United Kingdom | GB | Exact |
| Cockayne syndrome | Prevalence at birth | 1-9 / 1 000 000 | United Kingdom | GB | Exact |
| Cockayne syndrome | Annual incidence | 1-9 / 1 000 000 | Europe | Not stated | Exact |
| Cockayne syndrome | Annual incidence | 1-9 / 1 000 000 | Europe | Not stated | Exact |
Showing 5 of 24 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Cockayne syndrome | 191 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Cockayne syndrome | 191 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.