Condition (MeSH)
Corneal Ulcer
ClinicalTrials.gov lists 55 trials for Corneal Ulcer or a narrower condition beneath it.
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Trials per phase
55 of the 55 trials are tagged with Corneal Ulcer itself; the rest are tagged with a narrower condition beneath it.
When did Corneal Ulcer trials start? (22)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 3 |
| 2024 | 3 |
| 2023 | 4 |
| 2022 | 4 |
| 2021 | 4 |
| 2020 | 4 |
| 2019 | 2 |
| 2018 | 1 |
| 2016 | 2 |
Showing 10 of 22 earlier years.
No forecast is made for this condition: it averages 3.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 31 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 23 months across 35 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Corneal Ulcer trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 5 |
| Phase 1/2 | 2 |
| Phase 2 | 7 |
| Phase 2/3 | 2 |
| Phase 3 | 7 |
| Phase 4 | 3 |
| Not applicable | 16 |
| Observational | 13 |
How many Corneal Ulcer trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 5 |
| Completed | 29 |
| Terminated | 3 |
| Withdrawn | 5 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Corneal Ulcer trials? (7)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Dompé Farmaceutici S.p.A | 2 |
| Peschke GmbH | 2 |
| TBF Genie Tissulaire | 2 |
| ACRO Biomedical Co. Ltd | 1 |
| Alaa Gamal | 1 |
Showing 5 of 7 sponsors.
Which drugs are being tested for Corneal Ulcer? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Natamycin | 2 |
Interventions as named in the registry (14)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Voriconazole 1% | 3 |
| Topical Corticosteroid | 2 |
| Anti-Rejection Agents | 1 |
| Adjunctive Topical Fluorometholone (FML) 0.1% | 1 |
| OXERVATE® 0.002% | 1 |
Showing 5 of 14 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Corneal Ulcer trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Therapeutic penetrating keratoplasty | 64 | 2 |
| Corneal perforation and/or TPK | 52 | 1 |
| Corneal perforation | 41 | 3 |
| Death | 14 | 2 |
| Perforation | 11 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Corneal Ulcer? (113)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Factors Associated with Vision Outcomes in Microbial Keratitis: A Multisite Prospective Cohort Study. | Ophthalmology | 2025 | Yes |
| Steroids in the Management of Infectious Keratitis. | Cornea | 2023 | Yes |
| Patterns of Antifungal Resistance in Adult Patients With Fungal Keratitis in South India: A Post Hoc Analysis of 3 Randomized Clinical Trials. | JAMA ophthalmology | 2022 | Yes |
| Village-integrated eye workers for prevention of corneal ulcers in Nepal (VIEW study): a cluster-randomised controlled trial. | The Lancet. Global health | 2022 | Yes |
| Infectious keratitis: A review. | Clinical & experimental ophthalmology | 2022 | Yes |
Showing 5 of 113 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.