Condition (MeSH)
Cystinuria
ClinicalTrials.gov lists 21 trials for Cystinuria or a narrower condition beneath it. Advicenne Pharma has the most among industry and government lead sponsors, with 2.
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Trials per phase
21 of the 21 trials are tagged with Cystinuria itself; the rest are tagged with a narrower condition beneath it.
When did Cystinuria trials start? (13)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 4
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2024 | 2 |
| 2023 | 1 |
| 2021 | 2 |
| 2018 | 2 |
| 2017 | 3 |
| 2016 | 2 |
| 2015 | 1 |
| 2013 | 2 |
| 2012 | 2 |
| 2009 | 1 |
Showing 10 of 13 earlier years.
No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Cystinuria trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 1 |
| Phase 2 | 5 |
| Phase 2/3 | 2 |
| Phase 4 | 1 |
| Not applicable | 3 |
| Observational | 9 |
How many Cystinuria trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 5 |
| Active, not recruiting | 1 |
| Completed | 10 |
| Withdrawn | 3 |
| Unknown status | 2 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Cystinuria trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Advicenne Pharma | 2 |
| Devicare S.L. | 1 |
| Revive Therapeutics, Ltd. | 1 |
Which drugs are being tested for Cystinuria? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| BMS-512148 | 2 |
| Tiopronin | 1 |
| Bucillamine | 1 |
Interventions as named in the registry (7)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| ADV7103 | 2 |
| Tiopronin 2g per day | 1 |
| Tiopronin 1g per day | 1 |
| Tiopronin 3g per day | 1 |
| Tolvaptan IR | 1 |
Showing 5 of 7 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Cystinuria? (14)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Donor-transmitted cystinuria in a renal transplant recipient. | Journal of nephrology | 2024 | Yes |
| Cystine Stone Formers Have Impaired Health-Related Quality of Life Compared with Noncystine Stone Formers: A Case-Referent Study Piloting the Wisconsin Stone Quality of Life Questionnaire Among Patients with Cystine Stones. | Journal of endourology | 2017 | Yes |
| α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. | Nature medicine | 2017 | Yes |
| A new workflow for proteomic analysis of urinary exosomes and assessment in cystinuria patients. | Journal of proteome research | 2015 | Yes |
| CKD and Its Risk Factors among Patients with Cystinuria. | Clinical journal of the American Society of Nephrology : CJASN | 2015 | Yes |
Showing 5 of 14 publications.
Prevalence (27)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Cystinuria | Prevalence at birth | 1-5 / 10 000 | United Kingdom | GB | Exact |
| Cystinuria | Prevalence at birth | 1-5 / 10 000 | United Kingdom | GB | Unspecified |
| Cystinuria | Prevalence at birth | 1-5 / 10 000 | United Kingdom | GB | Exact |
| Cystinuria | Prevalence at birth | 1-9 / 100 000 | United States | US | Exact |
| Cystinuria | Prevalence at birth | 1-9 / 100 000 | United States | US | Unspecified |
Showing 5 of 27 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Cystinuria | 214 | Exact | Orphadata Science knowledge files, Product 1 |
| Cystinuria | 214 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.