Condition (MeSH)
De Lange Syndrome
ClinicalTrials.gov lists 8 trials for De Lange Syndrome or a narrower condition beneath it.
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Trials per phase
8 of the 8 trials are tagged with De Lange Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did De Lange Syndrome trials start? (7)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2/3
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 1 |
| 2024 | 2 |
| 2023 | 1 |
| 2018 | 1 |
| 2016 | 1 |
| 2010 | 1 |
No forecast is made for this condition: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are De Lange Syndrome trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 1 |
| Phase 2/3 | 1 |
| Not applicable | 2 |
| Observational | 4 |
How many De Lange Syndrome trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 5 |
| Terminated | 1 |
| Unknown status | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which publications cover De Lange Syndrome? (6)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| A Behavioural Assessment of Social Anxiety and Social Motivation in Fragile X, Cornelia de Lange and Rubinstein-Taybi Syndromes. | Journal of autism and developmental disorders | 2020 | Yes |
| Hidden mutations in Cornelia de Lange syndrome limitations of sanger sequencing in molecular diagnostics. | Human mutation | 2015 | Yes |
| Effects of social context on social interaction and self-injurious behavior in Cornelia de Lange syndrome. | American journal of mental retardation : AJMR | 2006 | Yes |
| The association between environmental events and self-injurious behaviour in Cornelia de Lange syndrome. | Journal of intellectual disability research : JIDR | 2005 | Yes |
| Mild Brachmann-de Lange syndrome. Delineation of the clinical phenotype, and characteristic behaviors in a six-year-old boy. | American journal of medical genetics | 1993 | Yes |
Showing 5 of 6 publications.
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Cornelia de Lange syndrome | Prevalence at birth | 1-9 / 1 000 000 | France | Not stated | Exact |
| Cornelia de Lange syndrome | Point prevalence | 1-9 / 1 000 000 | Denmark | Not stated | Exact |
| Cornelia de Lange syndrome | Prevalence at birth | 1-9 / 100 000 | Europe | Not stated | Exact |
| Cornelia de Lange syndrome | Point prevalence | 1-9 / 1 000 000 | Denmark | Not stated | Exact |
| Cornelia de Lange syndrome | Prevalence at birth | 1-9 / 1 000 000 | France | Not stated | Exact |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Cornelia de Lange syndrome | 199 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Cornelia de Lange syndrome | 199 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: lead sponsors, serious adverse events in this condition's trials, and sub-conditions in mesh.
Not computed for conditions with fewer than 10 trials: drugs tested.