Condition (MeSH)
Dental Calculus
ClinicalTrials.gov lists 18 trials for Dental Calculus or a narrower condition beneath it. Home Skinovations Ltd. has the most among industry and government lead sponsors, with 3.
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Trials per phase
18 of the 18 trials are tagged with Dental Calculus itself; the rest are tagged with a narrower condition beneath it.
When did Dental Calculus trials start? (10)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 2/3
- Phase 3
- Not applicable
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2023 | 2 |
| 2022 | 2 |
| 2021 | 2 |
| 2020 | 2 |
| 2019 | 4 |
| 2018 | 1 |
| 2017 | 2 |
| 2010 | 1 |
| 2006 | 1 |
No forecast is made for this condition: it averages 1.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 18 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Dental Calculus trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 1 |
| Phase 2/3 | 1 |
| Phase 3 | 1 |
| Not applicable | 13 |
| Observational | 2 |
How many Dental Calculus trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Completed | 12 |
| Withdrawn | 1 |
| Unknown status | 4 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Dental Calculus trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Home Skinovations Ltd. | 3 |
| Colgate Palmolive | 1 |
| Pontis Biologics, Inc. | 1 |
Interventions as named in the registry (7)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Tartarase | 1 |
| Control (placebo) group | 1 |
| 0.76% sodium monofluorophosphate | 1 |
| Chlorhexidine mouthwash | 1 |
| 0.454% stannous fluoride | 1 |
Showing 5 of 7 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Dental Calculus? (59)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Control of dental calculus Prevents severe Radiation-Induced oral mucositis in patients undergoing radiotherapy for nasopharyngeal carcinoma. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology | 2025 | Yes |
| A proof of principle investigation of a novel enzyme formulation on dental calculus deposition: a 4-week randomized human clinical trial. | BMC oral health | 2024 | Yes |
| Recent advances in the pathogenesis and prevention strategies of dental calculus. | NPJ biofilms and microbiomes | 2024 | Yes |
| Salivary Levels of IL-6 and IL-17 Could Be an Indicator of Disease Severity in Patients with Calculus Associated Chronic Periodontitis. | BioMed research international | 2018 | Yes |
| Anti-calculus and whitening toothpastes. | Monographs in oral science | 2013 | Yes |
Showing 5 of 59 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.