Condition (MeSH)
Dyspepsia
ClinicalTrials.gov lists 256 trials for Dyspepsia or a narrower condition beneath it. Novartis has the most among industry and government lead sponsors, with 7.
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Trials per phase
256 of the 256 trials are tagged with Dyspepsia itself; the rest are tagged with a narrower condition beneath it.
When did Dyspepsia trials start? (28)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 18
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 9 |
| 2025 | 14 |
| 2024 | 14 |
| 2023 | 12 |
| 2022 | 18 |
| 2021 | 9 |
| 2020 | 12 |
| 2019 | 12 |
| 2018 | 8 |
| 2017 | 10 |
Showing 10 of 28 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 12 trials starting in 2026 and about 14 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 34 months from start to primary completion across 15 trials still running at the 2026-10-09 snapshot; registered median of 16 months across 150 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Dyspepsia trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 9 |
| Phase 1/2 | 7 |
| Phase 2 | 16 |
| Phase 2/3 | 6 |
| Phase 3 | 36 |
| Phase 4 | 42 |
| Not applicable | 92 |
| Observational | 48 |
How many Dyspepsia trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 8 |
| Recruiting | 24 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 5 |
| Completed | 153 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Dyspepsia trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Novartis | 7 |
| Forest Laboratories | 5 |
| AstraZeneca | 3 |
Which drugs are being tested for Dyspepsia? (10)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Amoxicillin | 10 |
| Natrol | 9 |
| Omeprazole 20 mg | 7 |
| Tegaserod | 6 |
| Domperidone | 5 |
Showing 5 of 10 drugs.
Interventions as named in the registry (5)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Nexium Pill | 19 |
| Clarithromycin XL | 10 |
| Famotidine FCT | 3 |
| Ranitidine hydrochloride ODT | 3 |
| Diet | 3 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Dyspepsia trials report? (8)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Abdominal Distension | 3 | 1 |
| Abdominal lacerations | 1 | 1 |
| Acute Encephalopathy | 1 | 1 |
| Anemia of Grade 3 | 1 | 1 |
| Appendectomy | 1 | 1 |
Showing 5 of 8 adverse events.
Which publications cover Dyspepsia? (412)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Clinical Trial: Treatment of Functional Dyspepsia According to Subtype Compared With Empirical Proton Pump Inhibitor. | Alimentary pharmacology & therapeutics | 2025 | Yes |
| Efficacy of Linaclotide in Functional Dyspepsia and Constipation-Predominant Irritable Bowel Syndrome Overlap: A Randomized Trial. | Journal of gastroenterology and hepatology | 2025 | Yes |
| Randomized trial of the effect of esomeprazole on functional dyspepsia during Ramadan fasting. | Scientific reports | 2025 | Yes |
| A randomized, three-way crossover clinical trial on the efficacy of Mastiha based therapies (Pistacia lentiscus var. Chia) in functional dyspepsia. | Pharmacological research | 2025 | Yes |
| Transcutaneous Auricular Vagal Nerve Stimulation Is Effective for the Treatment of Functional Dyspepsia: A Multicenter, Randomized Controlled Study. | The American journal of gastroenterology | 2024 | Yes |
Showing 5 of 412 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.