Condition (MeSH)
Dyspnea
ClinicalTrials.gov lists 881 trials for Dyspnea or a narrower condition beneath it. Novartis Pharmaceuticals has the most among industry and government lead sponsors, with 13.
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Trials per phase (log scale)
874 of the 881 trials are tagged with Dyspnea itself; the rest are tagged with a narrower condition beneath it.
When did Dyspnea trials start? (30)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 3 trials are registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 82
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 63 |
| 2025 | 68 |
| 2024 | 59 |
| 2023 | 82 |
| 2022 | 45 |
| 2021 | 50 |
| 2020 | 55 |
| 2019 | 41 |
| 2018 | 41 |
| 2017 | 35 |
Showing 10 of 30 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 77 trials starting in 2026 and about 67 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 28 months from start to primary completion across 59 trials still running at the 2026-10-09 snapshot; registered median of 16 months across 554 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Dyspnea trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 17 |
| Phase 1/2 | 14 |
| Phase 2 | 55 |
| Phase 2/3 | 9 |
| Phase 3 | 38 |
| Phase 4 | 39 |
| Not applicable | 440 |
| Observational | 269 |
How many Dyspnea trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 53 |
| Recruiting | 92 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 20 |
| Completed | 503 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Dyspnea trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Novartis Pharmaceuticals | 13 |
Which drugs are being tested for Dyspnea? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| FENTANYL | 8 |
| Nitric Oxide | 5 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Furosemide-IR | 8 |
| PO Morphine | 8 |
| Nesritide (2+0.01) | 6 |
| Salbutamol MDI | 4 |
| Tiotropium bromide via (Spiriva® Handihaler®) | 4 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Dyspnea trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Asthma | 91 | 2 |
| Pneumonia | 39 | 10 |
| Heart Failure Decompensation | 38 | 1 |
| Other: Battery at Elective Replacement Indicator | 32 | 1 |
| asthma | 30 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Dyspnea? (1,745)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Management of Dyspnea With High-Flow Nasal Air or Fan-A Randomized Controlled Crossover Trial. | Journal of pain and symptom management | 2026 | Yes |
| Identifying Abnormal Exertional Breathlessness in COPD: Comparing Modified Medical Research Council and COPD Assessment Test With Cardiopulmonary Exercise Testing. | Chest | 2025 | Yes |
| Impact of upper extremity robotic rehabilitation on respiratory parameters, functional capacity and dyspnea in patients with stroke: a randomized controlled study. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology | 2025 | Yes |
| Impact of functional re-education and environmental adaptation in cancer patients with respiratory pathology: Study protocol. | PloS one | 2025 | Yes |
| Artificial Intelligence-Guided Lung Ultrasound by Nonexperts. | JAMA cardiology | 2025 | Yes |
Showing 5 of 1,745 publications.
Sub-conditions in MeSH (2)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.