Condition (MeSH)
Encephalomalacia
ClinicalTrials.gov lists 41 trials for Encephalomalacia or a narrower condition beneath it. NICHD Neonatal Research Network has the most among industry and government lead sponsors, with 2.
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Trials per phase
2 of the 41 trials are tagged with Encephalomalacia itself; the rest are tagged with a narrower condition beneath it.
When did Encephalomalacia trials start? (24)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 2 |
| 2024 | 1 |
| 2023 | 1 |
| 2022 | 1 |
| 2021 | 2 |
| 2020 | 2 |
| 2019 | 1 |
| 2018 | 1 |
| 2017 | 4 |
Showing 10 of 24 earlier years.
No forecast is made for this condition: it averages 1.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Encephalomalacia trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 3 |
| Phase 2 | 5 |
| Phase 2/3 | 1 |
| Phase 3 | 7 |
| Phase 4 | 1 |
| Not applicable | 12 |
| Observational | 10 |
How many Encephalomalacia trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 2 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 1 |
| Completed | 22 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Encephalomalacia trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| NICHD Neonatal Research Network | 2 |
| Draeger Medical Systems, Inc. | 1 |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1 |
Which drugs are being tested for Encephalomalacia? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| EPOETIN ALFA | 2 |
Interventions as named in the registry (14)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Recombinant Human Erythropoietin | 2 |
| Lactobacillus rhamnosus GR1 and Lactobacillus reuteri RC-14 | 1 |
| Dextrose 5 | 1 |
| UDI-001 | 1 |
| Progesterone 8% | 1 |
Showing 5 of 14 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Encephalomalacia trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Need for Surgical or Catheter-Based Intervention | 87 | 1 |
| Symptomatic patent ductus arteriosis (PDA) | 86 | 1 |
| Pulmonary interstitial emphysema (PIE) | 45 | 1 |
| Necrotizing enterocolitis (NEC) of Bell's stage 2 severity or greater | 33 | 1 |
| Severe IVH/PVL | 29 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Encephalomalacia? (4)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Neuropsychiatric significance of subcortical hyperintensity. | The Journal of neuropsychiatry and clinical neurosciences | 2001 | Yes |
| The ketogenic diet for medically and surgically refractory status epilepticus in the neurocritical care unit. | Neurocritical care | 2011 | No |
| Cortical reorganization induced by virtual reality therapy in a child with hemiparetic cerebral palsy. | Developmental medicine and child neurology | 2005 | No |
| [Epidemiology of cerebral vascular occlusions]. | Verhandlungen der Deutschen Gesellschaft fur Innere Medizin | 1972 | No |
Sub-conditions in MeSH (1)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.