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Condition (MeSH)

Encopresis

ClinicalTrials.gov lists 107 trials for Encopresis or a narrower condition beneath it.

MeSH D004688 Pathological Conditions, Signs and Symptoms C23 F03
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Phase 1 Phase 1 4 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 2 Phase 3 Phase 3 7 Phase 4 Phase 4 4 Not applicable Not applicable 50 Observational Observational 38 Phase 1 Phase 1 4 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 2 Phase 3 Phase 3 7 Phase 4 Phase 4 4 Not applicable Not applicable 50 Observational Observational 38

Trials per phase (log scale)

107 of the 107 trials are tagged with Encopresis itself; the rest are tagged with a narrower condition beneath it.

Get the Encopresis report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Encopresis trials start? (23)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 10

2002: 1 trials (Phase 1 1) 2003: 1 trials (Not applicable 1) 2006: 2 trials (Not applicable 2) 2007: 3 trials (Phase 3 2, Phase 1 1) 2008: 1 trials (Not applicable 1) 2009: 2 trials (Not applicable 2) 2010: 3 trials (Observational 1, Not applicable 2) 2011: 3 trials (Observational 1, Not applicable 1, Phase 3 1) 2012: 5 trials (Observational 1, Not applicable 2, Phase 3 1, Phase 2 1) 2013: 6 trials (Not applicable 3, Phase 4 1, Phase 1/2 2) 2014: 2 trials (Observational 1, Not applicable 1) 2015: 5 trials (Observational 1, Not applicable 4) 2016: 4 trials (Observational 2, Not applicable 2) 2017: 10 trials (Observational 2, Not applicable 7, Phase 3 1) 2018: 6 trials (Observational 3, Not applicable 3) 2019: 6 trials (Observational 5, Phase 2 1) 2020: 8 trials (Observational 4, Not applicable 2, Phase 3 1, Phase 1 1) 2021: 8 trials (Observational 5, Not applicable 3) 2022: 6 trials (Observational 3, Not applicable 1, Phase 4 1, Phase 1 1) 2023: 5 trials (Observational 2, Not applicable 3) 2024: 9 trials (Observational 6, Not applicable 1, Phase 4 1, Phase 3 1) 2025: 6 trials (Observational 1, Not applicable 5)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 5
2025 6
2024 9
2023 5
2022 6
2021 8
2020 8
2019 6
2018 6
2017 10

Forecast of the full-year count, planned starts included, not rows of this table: about 5 trials starting in 2026 and about 6 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. The 2026 forecast is below the 5 already registered with a 2026 start date: at the cutoff, 2 trials were already registered to start in October to December, more than the method's monthly average allows for, and the method does not use those planned starts.

Prediction, not a registry value: median of 36 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 25 months across 71 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Encopresis trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 4
Phase 1/2 2
Phase 2 2
Phase 3 7
Phase 4 4
Not applicable 50
Observational 38

How many Encopresis trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 6
Recruiting 11
Enrolling by invitation 1
Active, not recruiting 7
Completed 57

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Encopresis trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
James J. Peters Veterans Affairs Medical Center 3
Norgine 3
Cook MyoSite 2
Manchester University NHS Foundation Trust 2

Which drugs are being tested for Encopresis? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Glycerin Suppository 3
Iltamiocel 2

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Combination of Neostigmine and Glycopyrrolate 3
Treatment As Usual 2
Infusion of mesenchymal stem cells from adipose tissue 1
NRL001 cream 2.0%w/w 1
Acupuncture 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Encopresis trials report? (7)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 2 1
Myocardial Infarction 1 1
Nephrotic syndrome 1 1
Sinus operation 1 1
Small intestine obstruction 1 1

Which publications cover Encopresis? (20)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
A Pilot Randomized Clinical Trial of a Multidisciplinary Intervention for Encopresis in Children with Autism Spectrum Disorder. Journal of autism and developmental disorders 2020 Yes
Encopresis, soiling and constipation in children and adults with developmental disability. Research in developmental disabilities 2009 Yes
Fiber (glucomannan) is beneficial in the treatment of childhood constipation. Pediatrics 2004 Yes
Functional fecal retention with encopresis in childhood. Journal of pediatric gastroenterology and nutrition 2004 Yes
Childhood constipation: is there new light in the tunnel? Journal of pediatric gastroenterology and nutrition 2004 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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