Condition (MeSH)
Endocardial Cushion Defects
ClinicalTrials.gov lists 8 trials for Endocardial Cushion Defects or a narrower condition beneath it. National Heart, Lung, and Blood Institute (NHLBI) has the most among industry and government lead sponsors, with 2.
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Trials per phase
8 of the 8 trials are tagged with Endocardial Cushion Defects itself; the rest are tagged with a narrower condition beneath it.
When did Endocardial Cushion Defects trials start? (8)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1/2
- Phase 2
- Phase 3
- Observational
Top of scale: 1
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2019 | 1 |
| 2017 | 1 |
| 2008 | 1 |
| 2005 | 1 |
| 2003 | 1 |
| 2001 | 1 |
| 1999 | 1 |
| 1990 | 1 |
No forecast is made for this condition: it averages 0.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 8 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Endocardial Cushion Defects trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 1 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Observational | 4 |
How many Endocardial Cushion Defects trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 1 |
| Completed | 5 |
| Terminated | 1 |
| Unknown status | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Endocardial Cushion Defects trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Heart, Lung, and Blood Institute (NHLBI) | 2 |
Which serious adverse events do Endocardial Cushion Defects trials report? (1)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Morbidity | 2 | 1 |
Which publications cover Endocardial Cushion Defects? (6)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Identification of a complex congenital heart defect susceptibility locus by using DNA pooling and shared segment analysis. | Human molecular genetics | 1997 | Yes |
| Linkage analysis of autosomal dominant atrioventricular canal defects: exclusion of chromosome 21. | Human genetics | 1994 | Yes |
| Endocardial cushion defect: further studies of "isolated" versus "syndromic" occurrence. | American journal of medical genetics | 1992 | Yes |
| Down's syndrome affects results of surgical correction of complete atrioventricular canal. | Pediatric cardiology | 1992 | Yes |
| Acute-phase responses to cardiopulmonary bypass in children weighing less than 10 kilograms. | The Annals of thoracic surgery | 1996 | No |
Showing 5 of 6 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.
Not computed for conditions with fewer than 10 trials: drugs tested.