Condition (MeSH)
Focal Dermal Hypoplasia
ClinicalTrials.gov lists 3 trials for Focal Dermal Hypoplasia or a narrower condition beneath it. AstraZeneca has the most among industry and government lead sponsors, with 1.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
3 of the 3 trials are tagged with Focal Dermal Hypoplasia itself; the rest are tagged with a narrower condition beneath it.
When did Focal Dermal Hypoplasia trials start? (3)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Observational
Top of scale: 1
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2021 | 1 |
| 2015 | 1 |
| 2007 | 1 |
No forecast is made for this condition: it averages 0.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 3 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Focal Dermal Hypoplasia trials in? (2)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Observational | 2 |
How many Focal Dermal Hypoplasia trials are recruiting? (2)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Active, not recruiting | 1 |
| Completed | 2 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Focal Dermal Hypoplasia trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| AstraZeneca | 1 |
Which publications cover Focal Dermal Hypoplasia? (6)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia. | Nature genetics | 2007 | Yes |
| Microphthalmia with linear skin defects (MLS), Aicardi, and Goltz syndromes: are they related X-linked dominant male-lethal disorders? | Cytogenetic and genome research | 2002 | Yes |
| Focal dermal hypoplasia syndrome. An update. | Archives of dermatology | 1992 | Yes |
| Focal dermal hypoplasia. | Archives of dermatology | 1962 | Yes |
| A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cells. | Cell reports | 2014 | No |
Showing 5 of 6 publications.
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Focal dermal hypoplasia | Point prevalence | <1 / 1 000 000 | Worldwide | Not stated | Exact |
| Focal dermal hypoplasia | Point prevalence | <1 / 1 000 000 | Worldwide | Not stated | Exact |
| Focal dermal hypoplasia | Cases families | Worldwide | Not stated | Exact | |
| Focal dermal hypoplasia | Cases families | Worldwide | Not stated | Exact | |
| Focal dermal hypoplasia | Point prevalence | <1 / 1 000 000 | Worldwide | Not stated | Unspecified |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Focal dermal hypoplasia | 2092 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Focal dermal hypoplasia | 2092 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.
Not computed for conditions with fewer than 10 trials: drugs tested.