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Condition (MeSH)

Growth Disorders

ClinicalTrials.gov lists 469 trials for Growth Disorders or a narrower condition beneath it. Merck KGaA, Darmstadt, Germany has the most among industry and government lead sponsors, with 20.

MeSH D006130 Pathological Conditions, Signs and Symptoms C23 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 9 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 14 Phase 2/3 Phase 2/3 12 Phase 3 Phase 3 37 Phase 4 Phase 4 9 Not applicable Not applicable 165 Observational Observational 221 Phase 1 Phase 1 9 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 14 Phase 2/3 Phase 2/3 12 Phase 3 Phase 3 37 Phase 4 Phase 4 9 Not applicable Not applicable 165 Observational Observational 221

Trials per phase (log scale)

1 more section with rows

214 of the 469 trials are tagged with Growth Disorders itself; the rest are tagged with a narrower condition beneath it.

Get the Growth Disorders report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Growth Disorders trials start? (34)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 38

1990: 2 trials (Not applicable 1, Phase 3 1) 1993: 2 trials (Phase 3 2) 1994: 1 trials (Observational 1) 1995: 1 trials (Observational 1) 1996: 1 trials (Not applicable 1) 1997: 2 trials (Observational 2) 1998: 1 trials (Observational 1) 2000: 3 trials (Observational 1, Not applicable 1, Phase 3 1) 2001: 3 trials (Observational 1, Phase 3 2) 2002: 1 trials (Observational 1) 2003: 6 trials (Observational 3, Not applicable 1, Phase 3 2) 2004: 4 trials (Phase 3 1, Phase 2 2, Phase 1 1) 2005: 4 trials (Observational 1, Phase 3 2, Phase 2/3 1) 2006: 7 trials (Observational 4, Not applicable 1, Phase 4 1, Phase 3 1) 2007: 5 trials (Observational 4, Not applicable 1) 2008: 5 trials (Observational 1, Not applicable 2, Phase 3 1, Phase 2/3 1) 2009: 7 trials (Observational 2, Not applicable 2, Phase 3 2, Phase 1 1) 2010: 11 trials (Observational 6, Not applicable 5) 2011: 22 trials (Observational 12, Not applicable 6, Phase 4 2, Phase 3 1, Phase 1 1) 2012: 13 trials (Observational 6, Not applicable 4, Phase 4 1, Phase 2/3 1, Phase 2 1) 2013: 16 trials (Observational 8, Not applicable 4, Phase 3 2, Phase 1 2) 2014: 21 trials (Observational 11, Not applicable 6, Phase 4 1, Phase 2/3 1, Phase 2 2) 2015: 25 trials (Observational 10, Not applicable 6, Phase 3 4, Phase 2/3 3, Phase 2 2) 2016: 26 trials (Observational 14, Not applicable 9, Phase 3 1, Phase 2/3 1, Phase 2 1) 2017: 22 trials (Observational 7, Not applicable 10, Phase 3 3, Phase 2/3 2) 2018: 38 trials (Observational 9, Not applicable 25, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 1 1) 2019: 22 trials (Observational 12, Not applicable 8, Phase 3 2) 2020: 31 trials (Observational 16, Not applicable 14, Phase 3 1) 2021: 37 trials (Observational 19, Not applicable 15, Phase 4 1, Phase 3 1, Phase 1 1) 2022: 30 trials (Observational 16, Not applicable 8, Phase 4 1, Phase 3 2, Phase 2/3 1, Phase 2 1, Phase 1 1) 2023: 29 trials (Observational 15, Not applicable 9, Phase 3 2, Phase 2 1, Phase 1/2 1, Phase 1 1) 2024: 27 trials (Observational 18, Not applicable 9) 2025: 22 trials (Observational 8, Not applicable 10, Phase 4 1, Phase 3 1, Phase 2 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 19
2025 22
2024 27
2023 29
2022 30
2021 37
2020 31
2019 22
2018 38
2017 22

Forecast of the full-year count, planned starts included, not rows of this table: about 24 trials starting in 2026 and about 23 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 30 trials still running at the 2026-10-09 snapshot; registered median of 25 months across 277 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Growth Disorders trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 9
Phase 1/2 1
Phase 2 14
Phase 2/3 12
Phase 3 37
Phase 4 9
Not applicable 165
Observational 221
Expanded access 1

How many Growth Disorders trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 19
Recruiting 54
Enrolling by invitation 5
Active, not recruiting 15
Completed 249

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Growth Disorders trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Merck KGaA, Darmstadt, Germany 20
Novo Nordisk A/S 8
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 6

Which drugs are being tested for Growth Disorders? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
SILDENAFIL 7
LOVENOX 5
Somavaratan 3

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
somatropin AQ 17
EC Aspirin 10
Control (placebo) group 3
Melatonin PR 3
BLOOD SAMPLE 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Growth Disorders trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Scoliosis 78 1
Seizure 78 1
Craniopharyngioma 76 1
Headache 75 1
Epiphysiolysis 73 1

Which publications cover Growth Disorders? (608)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages