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Condition (MeSH)

Hepatitis C

ClinicalTrials.gov lists 2,308 trials for Hepatitis C or a narrower condition beneath it. Merck Sharp & Dohme LLC has the most among industry and government lead sponsors, with 163.

MeSH D006526 Infections C01 C06
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Phase 1 Phase 1 290 Phase 1/2 Phase 1/2 57 Phase 2 Phase 2 379 Phase 2/3 Phase 2/3 45 Phase 3 Phase 3 347 Phase 4 Phase 4 294 Not applicable Not applicable 299 Observational Observational 591 Phase 1 Phase 1 290 Phase 1/2 Phase 1/2 57 Phase 2 Phase 2 379 Phase 2/3 Phase 2/3 45 Phase 3 Phase 3 347 Phase 4 Phase 4 294 Not applicable Not applicable 299 Observational Observational 591

Trials per phase

1 more section with rows

1,719 of the 2,308 trials are tagged with Hepatitis C itself; the rest are tagged with a narrower condition beneath it.

Get the Hepatitis C report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hepatitis C trials start? (34)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 168

1991: 1 trials (Observational 1) 1992: 1 trials (Observational 1) 1993: 2 trials (Observational 1, Phase 3 1) 1994: 1 trials (Observational 1) 1997: 3 trials (Observational 1, Phase 3 1, Phase 2/3 1) 1998: 4 trials (Observational 2, Phase 3 1, Phase 2 1) 1999: 5 trials (Observational 4, Phase 4 1) 2000: 12 trials (Observational 3, Phase 4 1, Phase 3 4, Phase 2 4) 2001: 20 trials (Observational 5, Not applicable 1, Phase 4 2, Phase 3 1, Phase 2 7, Phase 1/2 2, Phase 1 2) 2002: 41 trials (Observational 4, Phase 4 11, Phase 3 16, Phase 2/3 2, Phase 2 8) 2003: 46 trials (Observational 6, Not applicable 4, Phase 4 15, Phase 3 10, Phase 2 5, Phase 1/2 4, Phase 1 2) 2004: 59 trials (Observational 15, Not applicable 4, Phase 4 14, Phase 3 11, Phase 2/3 1, Phase 2 10, Phase 1/2 2, Phase 1 2) 2005: 100 trials (Observational 27, Not applicable 8, Phase 4 24, Phase 3 11, Phase 2/3 1, Phase 2 21, Phase 1/2 2, Phase 1 6) 2006: 85 trials (Observational 18, Not applicable 7, Phase 4 16, Phase 3 11, Phase 2/3 3, Phase 2 18, Phase 1/2 2, Phase 1 10) 2007: 102 trials (Observational 19, Not applicable 10, Phase 4 19, Phase 3 10, Phase 2/3 2, Phase 2 22, Phase 1/2 3, Phase 1 17) 2008: 102 trials (Observational 22, Not applicable 8, Phase 4 11, Phase 3 12, Phase 2 20, Phase 1/2 6, Phase 1 23) 2009: 127 trials (Observational 23, Not applicable 9, Phase 4 10, Phase 3 9, Phase 2/3 1, Phase 2 32, Phase 1/2 5, Phase 1 38) 2010: 118 trials (Observational 25, Not applicable 4, Phase 4 9, Phase 3 8, Phase 2/3 3, Phase 2 34, Phase 1/2 2, Phase 1 33) 2011: 168 trials (Observational 32, Not applicable 12, Phase 4 16, Phase 3 31, Phase 2/3 2, Phase 2 36, Phase 1/2 7, Phase 1 32) 2012: 166 trials (Observational 37, Not applicable 11, Phase 4 8, Phase 3 44, Phase 2/3 2, Phase 2 30, Phase 1/2 4, Phase 1 30) 2013: 134 trials (Observational 21, Not applicable 10, Phase 4 10, Phase 3 29, Phase 2/3 6, Phase 2 33, Phase 1/2 5, Phase 1 20) 2014: 138 trials (Observational 24, Not applicable 11, Phase 4 13, Phase 3 36, Phase 2/3 4, Phase 2 22, Phase 1/2 2, Phase 1 26) 2015: 155 trials (Observational 46, Not applicable 16, Phase 4 17, Phase 3 36, Phase 2/3 5, Phase 2 24, Phase 1/2 2, Phase 1 9) 2016: 132 trials (Observational 40, Not applicable 17, Phase 4 19, Phase 3 26, Phase 2/3 2, Phase 2 19, Phase 1/2 1, Phase 1 8) 2017: 125 trials (Observational 38, Not applicable 20, Phase 4 24, Phase 3 21, Phase 2/3 2, Phase 2 9, Phase 1/2 1, Phase 1 10) 2018: 101 trials (Observational 40, Not applicable 20, Phase 4 18, Phase 3 6, Phase 2/3 1, Phase 2 9, Phase 1/2 1, Phase 1 6) 2019: 103 trials (Observational 37, Not applicable 31, Phase 4 11, Phase 3 6, Phase 2/3 2, Phase 2 10, Phase 1/2 1, Phase 1 5) 2020: 53 trials (Observational 16, Not applicable 23, Phase 4 9, Phase 3 1, Phase 1/2 1, Phase 1 3) 2021: 36 trials (Observational 15, Not applicable 13, Phase 4 3, Phase 3 1, Phase 2/3 1, Phase 1/2 2, Phase 1 1) 2022: 42 trials (Observational 14, Not applicable 17, Phase 4 8, Phase 3 1, Phase 2 1, Phase 1 1) 2023: 36 trials (Observational 19, Not applicable 14, Phase 2/3 2, Phase 2 1) 2024: 25 trials (Observational 12, Not applicable 10, Phase 4 1, Phase 1 2) 2025: 18 trials (Observational 10, Not applicable 5, Phase 4 2, Phase 3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 16
2025 18
2024 25
2023 36
2022 42
2021 36
2020 53
2019 103
2018 101
2017 125

Forecast of the full-year count, planned starts included, not rows of this table: about 20 trials starting in 2026 and about 19 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 35 months from start to primary completion across 39 trials still running at the 2026-10-09 snapshot; registered median of 21 months across 1,763 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hepatitis C trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 290
Phase 1/2 57
Phase 2 379
Phase 2/3 45
Phase 3 347
Phase 4 294
Not applicable 299
Observational 591
Expanded access 6

How many Hepatitis C trials are recruiting? (12)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 23
Recruiting 44
Enrolling by invitation 5
Active, not recruiting 23
Available 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Hepatitis C trials? (13)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Merck Sharp & Dohme LLC 163
Gilead Sciences 119
AbbVie 91
Bristol-Myers Squibb 91
Hoffmann-La Roche 88

Which drugs are being tested for Hepatitis C? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
PEGinterferon alfa-2a 177
Peginterferon Alfa-2B 91
Daclatasvir 73
TMC435 67
Boceprevir 39

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Ribavirine 549
Sofosbuvir, Sovaldi 108
Telaprevir 54
Ritonavir (RTV) low 34
dasabuvir 8 weeks 31

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Hepatitis C trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Anaemia 622 118
Pneumonia 338 126
Hospitalization Events 216 1
Death 203 32
Depression 168 80

Which publications cover Hepatitis C? (1,370)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages