Condition (MeSH)
Heroin Dependence
ClinicalTrials.gov lists 90 trials for Heroin Dependence or a narrower condition beneath it. National Institute on Drug Abuse (NIDA) has the most among industry and government lead sponsors, with 13.
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Trials per phase
90 of the 90 trials are tagged with Heroin Dependence itself; the rest are tagged with a narrower condition beneath it.
When did Heroin Dependence trials start? (26)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 11
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2022 | 1 |
| 2021 | 2 |
| 2020 | 1 |
| 2019 | 5 |
| 2018 | 1 |
| 2017 | 1 |
| 2016 | 2 |
| 2015 | 3 |
| 2014 | 2 |
| 2013 | 5 |
Showing 10 of 26 earlier years.
No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Heroin Dependence trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 5 |
| Phase 1/2 | 3 |
| Phase 2 | 18 |
| Phase 2/3 | 5 |
| Phase 3 | 14 |
| Phase 4 | 6 |
| Not applicable | 22 |
| Observational | 17 |
How many Heroin Dependence trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Completed | 64 |
| Terminated | 3 |
| Withdrawn | 7 |
| Unknown status | 16 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Heroin Dependence trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute on Drug Abuse (NIDA) | 13 |
| L.Molteni & C. dei F.lli Alitti-Soc. di Esercizio S.p.A. | 2 |
Which drugs are being tested for Heroin Dependence? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Buprenorphine | 7 |
| Methadone | 3 |
| LAAM | 2 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| IM naltrexone | 10 |
| Buprenorphine and Naloxone | 6 |
| Hydromorphone ER | 3 |
| Opioid-Related Disorders | 3 |
| Heroin Dependence | 2 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Heroin Dependence trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| hospitalizations | 29 | 1 |
| Medical Event or Procedure | 13 | 1 |
| Death | 8 | 1 |
| Opioid Overdose | 8 | 1 |
| suicidal ideation | 4 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Heroin Dependence? (259)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 259 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.