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Condition (MeSH)

Hypospadias

ClinicalTrials.gov lists 108 trials for Hypospadias or a narrower condition beneath it.

MeSH D007021 Urogenital Diseases C12 C16 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 2 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 2 Phase 3 Phase 3 4 Phase 4 Phase 4 9 Not applicable Not applicable 65 Observational Observational 24 Phase 1 Phase 1 2 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 2 Phase 3 Phase 3 4 Phase 4 Phase 4 9 Not applicable Not applicable 65 Observational Observational 24

Trials per phase (log scale)

108 of the 108 trials are tagged with Hypospadias itself; the rest are tagged with a narrower condition beneath it.

Get the Hypospadias report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hypospadias trials start? (16)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 17

2011: 3 trials (Observational 2, Phase 3 1) 2012: 2 trials (Observational 2) 2013: 3 trials (Observational 2, Not applicable 1) 2014: 9 trials (Observational 1, Not applicable 6, Phase 4 1, Phase 2/3 1) 2015: 2 trials (Not applicable 2) 2016: 3 trials (Not applicable 2, Phase 4 1) 2017: 7 trials (Observational 1, Not applicable 3, Phase 4 2, Phase 2/3 1) 2018: 7 trials (Observational 2, Not applicable 4, Phase 2 1) 2019: 8 trials (Observational 4, Not applicable 3, Phase 1 1) 2020: 7 trials (Observational 3, Not applicable 3, Phase 3 1) 2021: 9 trials (Observational 2, Not applicable 4, Phase 3 1, Phase 1/2 1, Phase 1 1) 2022: 5 trials (Observational 1, Not applicable 4) 2023: 13 trials (Observational 1, Not applicable 9, Phase 4 3) 2024: 7 trials (Observational 1, Not applicable 6) 2025: 17 trials (Observational 2, Not applicable 13, Phase 4 1, Phase 3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 6
2025 17
2024 7
2023 13
2022 5
2021 9
2020 7
2019 8
2018 7
2017 7

Forecast of the full-year count, planned starts included, not rows of this table: about 8 trials starting in 2026 and about 13 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 34 months from start to primary completion across 12 trials still running at the 2026-10-09 snapshot; registered median of 15 months across 61 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hypospadias trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 2
Phase 1/2 1
Phase 2 1
Phase 2/3 2
Phase 3 4
Phase 4 9
Not applicable 65
Observational 24

How many Hypospadias trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 8
Recruiting 11
Enrolling by invitation 2
Active, not recruiting 3
Completed 54

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Hypospadias? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
+/- Bupivacaine HCl 4
DEXMEDETOMIDINE 3

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Caudal block 6
Caudal Block Anesthesia 5
Dorsal Penile Block Anesthesia 3
Ropivacaine 2 % 2
Caudal epidural block 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Hypospadias? (133)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages