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Condition (MeSH)

Urogenital Abnormalities

ClinicalTrials.gov lists 616 trials for Urogenital Abnormalities or a narrower condition beneath it. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) has the most among industry and government lead sponsors, with 18.

MeSH D014564 Urogenital Diseases C12 C16
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Phase 1 Phase 1 30 Phase 1/2 Phase 1/2 14 Phase 2 Phase 2 69 Phase 2/3 Phase 2/3 7 Phase 3 Phase 3 42 Phase 4 Phase 4 46 Not applicable Not applicable 166 Observational Observational 241 Phase 1 Phase 1 30 Phase 1/2 Phase 1/2 14 Phase 2 Phase 2 69 Phase 2/3 Phase 2/3 7 Phase 3 Phase 3 42 Phase 4 Phase 4 46 Not applicable Not applicable 166 Observational Observational 241

Trials per phase (log scale)

1 more section with rows

11 of the 616 trials are tagged with Urogenital Abnormalities itself; the rest are tagged with a narrower condition beneath it.

Get the Urogenital Abnormalities report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Urogenital Abnormalities trials start? (36)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 43

1990: 2 trials (Not applicable 1, Phase 2 1) 1992: 3 trials (Phase 4 1, Phase 3 1, Phase 2 1) 1993: 1 trials (Phase 2 1) 1994: 1 trials (Observational 1) 1995: 3 trials (Observational 1, Not applicable 1, Phase 3 1) 1996: 2 trials (Not applicable 1, Phase 4 1) 1997: 2 trials (Observational 1, Phase 3 1) 1998: 1 trials (Phase 3 1) 1999: 5 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 1, Phase 1 1) 2000: 4 trials (Observational 3, Phase 3 1) 2001: 6 trials (Observational 2, Not applicable 1, Phase 3 1, Phase 2 2) 2002: 4 trials (Observational 2, Not applicable 2) 2003: 2 trials (Observational 2) 2004: 6 trials (Observational 3, Phase 4 1, Phase 3 1, Phase 2 1) 2005: 11 trials (Observational 6, Phase 4 4, Phase 3 1) 2006: 13 trials (Observational 8, Not applicable 3, Phase 2 2) 2007: 15 trials (Observational 10, Not applicable 4, Phase 1/2 1) 2008: 10 trials (Observational 7, Not applicable 1, Phase 2 1, Phase 1 1) 2009: 15 trials (Observational 7, Not applicable 2, Phase 4 3, Phase 2/3 1, Phase 1 2) 2010: 17 trials (Observational 5, Not applicable 4, Phase 4 1, Phase 3 3, Phase 2 1, Phase 1/2 1, Phase 1 2) 2011: 15 trials (Observational 6, Not applicable 3, Phase 4 1, Phase 3 1, Phase 1 4) 2012: 32 trials (Observational 20, Not applicable 6, Phase 3 1, Phase 2/3 1, Phase 2 3, Phase 1 1) 2013: 23 trials (Observational 12, Not applicable 4, Phase 4 1, Phase 3 1, Phase 2 3, Phase 1/2 1, Phase 1 1) 2014: 27 trials (Observational 9, Not applicable 11, Phase 4 3, Phase 2/3 1, Phase 2 1, Phase 1/2 2) 2015: 22 trials (Observational 13, Not applicable 5, Phase 4 1, Phase 2 2, Phase 1 1) 2016: 28 trials (Observational 7, Not applicable 8, Phase 4 4, Phase 3 3, Phase 2 4, Phase 1 2) 2017: 28 trials (Observational 7, Not applicable 8, Phase 4 4, Phase 3 1, Phase 2/3 2, Phase 2 2, Phase 1 4) 2018: 28 trials (Observational 11, Not applicable 8, Phase 4 1, Phase 3 1, Phase 2 5, Phase 1/2 1, Phase 1 1) 2019: 27 trials (Observational 10, Not applicable 9, Phase 4 1, Phase 3 1, Phase 2 3, Phase 1 3) 2020: 23 trials (Observational 12, Not applicable 6, Phase 4 1, Phase 3 2, Phase 2 2) 2021: 43 trials (Observational 19, Not applicable 7, Phase 4 2, Phase 3 3, Phase 2 7, Phase 1/2 2, Phase 1 3) 2022: 32 trials (Observational 12, Not applicable 11, Phase 4 1, Phase 3 3, Phase 2 3, Phase 1/2 1, Phase 1 1) 2023: 35 trials (Observational 9, Not applicable 13, Phase 4 4, Phase 3 3, Phase 2 5, Phase 1/2 1) 2024: 38 trials (Observational 11, Not applicable 17, Phase 4 2, Phase 3 2, Phase 2 3, Phase 1/2 3) 2025: 43 trials (Observational 10, Not applicable 19, Phase 4 4, Phase 3 4, Phase 2/3 1, Phase 2 5)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 38
2025 43
2024 38
2023 35
2022 32
2021 43
2020 23
2019 27
2018 28
2017 28

Forecast of the full-year count, planned starts included, not rows of this table: about 46 trials starting in 2026 and about 42 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 52 trials still running at the 2026-10-09 snapshot; registered median of 29 months across 318 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Urogenital Abnormalities trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 30
Phase 1/2 14
Phase 2 69
Phase 2/3 7
Phase 3 42
Phase 4 46
Not applicable 166
Observational 241
Expanded access 1

How many Urogenital Abnormalities trials are recruiting? (10)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 32
Recruiting 102
Enrolling by invitation 9
Active, not recruiting 23
Completed 290

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Urogenital Abnormalities trials? (5)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 18
Novo Nordisk A/S 12
Neurocrine UK Limited 8
Rhythm Pharmaceuticals, Inc. 7
Natera, Inc. 6

Which drugs are being tested for Urogenital Abnormalities? (7)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
GnRH 8
Estradiol 7
Crinecerfont 6
Exenatide 5
DEXMEDETOMIDINE 4

Interventions as named in the registry (8)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
somatropin AQ 27
Hydrocortisone 1% 13
1% Metformin 12
Caudal block 7
Chronocort 7

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Urogenital Abnormalities trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Gastroenteritis 15 9
Vomiting 15 6
Pneumonia 13 8
Pyrexia 13 5
Sepsis 12 2

Which publications cover Urogenital Abnormalities? (66)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Three-dimensional transvaginal ultrasound versus MRI in the diagnosis and classification of congenital uterine anomalies: A systematic review and meta-analysis. European journal of obstetrics, gynecology, and reproductive biology 2025 Yes
LUMBAR Syndrome State-Of-The-Art Review: Insights Into a Rare and Complex Condition. Pediatric dermatology 2025 Yes
Determinants of the COVID-19 vaccine hesitancy spectrum. PloS one 2022 Yes
Prevalence of female sexual dysfunction during pregnancy in Eastern Mediterranean Regional Office Countries (EMRO): a systematic review and meta-analysis. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 Yes
Reverse phenotyping facilitates disease allele calling in exome sequencing of patients with CAKUT. Genetics in medicine : official journal of the American College of Medical Genetics 2022 Yes

Sub-conditions in MeSH (12)

MeSH descendants one level down with at least one trial, most trials first.

+2 more sub-conditions

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages