Condition (MeSH)
Lupus Erythematosus, Cutaneous
ClinicalTrials.gov lists 84 trials for Lupus Erythematosus, Cutaneous or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
64 of the 84 trials are tagged with Lupus Erythematosus, Cutaneous itself; the rest are tagged with a narrower condition beneath it.
When did Lupus Erythematosus, Cutaneous trials start? (26)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 9 |
| 2025 | 6 |
| 2024 | 4 |
| 2023 | 4 |
| 2022 | 7 |
| 2021 | 4 |
| 2020 | 3 |
| 2019 | 2 |
| 2018 | 1 |
| 2017 | 4 |
Showing 10 of 26 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 10 trials starting in 2026 and about 8 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 35 months from start to primary completion across 12 trials still running at the 2026-10-09 snapshot; registered median of 23 months across 51 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Lupus Erythematosus, Cutaneous trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 21 |
| Phase 1/2 | 2 |
| Phase 2 | 34 |
| Phase 2/3 | 2 |
| Phase 3 | 7 |
| Not applicable | 8 |
| Observational | 10 |
How many Lupus Erythematosus, Cutaneous trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 5 |
| Recruiting | 11 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 5 |
| Completed | 39 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Lupus Erythematosus, Cutaneous trials? (9)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Amgen | 4 |
| Biogen | 4 |
| EMD Serono Research & Development Institute, Inc. | 4 |
| Gilead Sciences | 4 |
| Bristol-Myers Squibb | 3 |
Showing 5 of 9 sponsors.
Which drugs are being tested for Lupus Erythematosus, Cutaneous? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Enpatoran | 4 |
| Litifilimab | 3 |
| Edecesertib | 2 |
| Daxdilimab | 2 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| X: Lenalidomide | 2 |
| 1=Etanercept | 2 |
| R932333 | 1 |
| ICP-488 Tablets | 1 |
| SOF-SKN 2% | 1 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Lupus Erythematosus, Cutaneous trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pneumonia | 5 | 3 |
| Systemic lupus erythematosus | 3 | 1 |
| Ankle fracture | 2 | 2 |
| Headache | 2 | 1 |
| Humerus fracture | 2 | 2 |
Showing 5 of 10 adverse events.
Which publications cover Lupus Erythematosus, Cutaneous? (38)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Enpatoran, a first-in-class, selective, orally administered toll-like receptor 7/8 inhibitor, in systemic and cutaneous lupus erythematosus: results from a randomised, placebo-controlled phase Ib study. | Lupus science & medicine | 2025 | Yes |
| Litifilimab (BIIB059), a promising investigational drug for cutaneous lupus erythematosus. | Expert opinion on investigational drugs | 2023 | Yes |
| Filgotinib or lanraplenib in moderate to severe cutaneous lupus erythematosus: a phase 2, randomized, double-blind, placebo-controlled study. | Rheumatology (Oxford, England) | 2022 | Yes |
| Trial of Anti-BDCA2 Antibody Litifilimab for Cutaneous Lupus Erythematosus. | The New England journal of medicine | 2022 | Yes |
| Safety, pharmacokinetics and pharmacodynamics of a topical SYK inhibitor in cutaneous lupus erythematosus: A double-blind Phase Ib study. | Experimental dermatology | 2021 | Yes |
Showing 5 of 38 publications.
Sub-conditions in MeSH (1)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.