Condition (MeSH)
Lupus Erythematosus, Discoid
ClinicalTrials.gov lists 41 trials for Lupus Erythematosus, Discoid or a narrower condition beneath it. EMD Serono Research & Development Institute, Inc. has the most among industry and government lead sponsors, with 4.
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Trials per phase (log scale)
41 of the 41 trials are tagged with Lupus Erythematosus, Discoid itself; the rest are tagged with a narrower condition beneath it.
When did Lupus Erythematosus, Discoid trials start? (20)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 4 |
| 2025 | 1 |
| 2024 | 2 |
| 2023 | 2 |
| 2022 | 6 |
| 2021 | 1 |
| 2019 | 2 |
| 2017 | 1 |
| 2016 | 2 |
| 2015 | 1 |
Showing 10 of 20 earlier years.
No forecast is made for this condition: it averages 2.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 23 months across 25 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Lupus Erythematosus, Discoid trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 6 |
| Phase 1/2 | 1 |
| Phase 2 | 20 |
| Phase 2/3 | 2 |
| Phase 3 | 5 |
| Not applicable | 2 |
| Observational | 5 |
How many Lupus Erythematosus, Discoid trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 3 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 5 |
| Completed | 18 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Lupus Erythematosus, Discoid trials? (11)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| EMD Serono Research & Development Institute, Inc. | 4 |
| Amgen | 3 |
| Biogen | 3 |
| Astion Pharma A/S | 2 |
| Bristol-Myers Squibb | 2 |
Showing 5 of 11 sponsors.
Which drugs are being tested for Lupus Erythematosus, Discoid? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Enpatoran | 3 |
| Litifilimab | 2 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| 1=Etanercept | 2 |
| R932333 | 1 |
| Anifrolumab SC infusion (600mg) | 1 |
| Ruxolitinib IR | 1 |
| Ruxolitinib 1.5% Cream | 1 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Lupus Erythematosus, Discoid trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pneumonia | 4 | 2 |
| Humerus fracture | 2 | 2 |
| Invasive ductal breast carcinoma | 2 | 1 |
| Abortion induced | 1 | 1 |
| Abortion induced incomplete | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Lupus Erythematosus, Discoid? (19)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Controversies in Systemic Lupus Erythematosus: Are We Treating Our Patients Adequately? | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases | 2022 | Yes |
| Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus. | Arthritis & rheumatology (Hoboken, N.J.) | 2017 | Yes |
| Long-term thalidomide use in refractory cutaneous lesions of lupus erythematosus: a 65 series of Brazilian patients. | Lupus | 2005 | Yes |
| The effects of daily stress and stressful life events on the clinical symptomatology of patients with lupus erythematosus. | Psychosomatic medicine | 2004 | Yes |
| Experience with low-dose thalidomide therapy in chronic discoid lupus erythematosus. | International journal of dermatology | 2000 | Yes |
Showing 5 of 19 publications.
Prevalence (9)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Discoid lupus erythematosus | Annual incidence | 1-9 / 100 000 | United States | US | Exact |
| Discoid lupus erythematosus | Annual incidence | 1-9 / 100 000 | United States | US | Unspecified |
| Discoid lupus erythematosus | Annual incidence | 1-9 / 100 000 | United States | US | Exact |
| Discoid lupus erythematosus | Annual incidence | 1-9 / 100 000 | Sweden | Not stated | Exact |
| Discoid lupus erythematosus | Point prevalence | 1-5 / 10 000 | Worldwide | Not stated | Exact |
Showing 5 of 9 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Discoid lupus erythematosus | 90281 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Discoid lupus erythematosus | 90281 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.