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Condition (MeSH)

Lymphopenia

ClinicalTrials.gov lists 93 trials for Lymphopenia or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 7.

MeSH D008231 Hemic and Lymphatic Diseases C15 C20
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Phase 1 Phase 1 9 Phase 1/2 Phase 1/2 12 Phase 2 Phase 2 24 Phase 3 Phase 3 4 Phase 4 Phase 4 2 Not applicable Not applicable 10 Observational Observational 31 Expanded access Expanded access 1 Phase 1 Phase 1 9 Phase 1/2 Phase 1/2 12 Phase 2 Phase 2 24 Phase 3 Phase 3 4 Phase 4 Phase 4 2 Not applicable Not applicable 10 Observational Observational 31 Expanded access Expanded access 1

Trials per phase (log scale)

42 of the 93 trials are tagged with Lymphopenia itself; the rest are tagged with a narrower condition beneath it.

Get the Lymphopenia report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Lymphopenia trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 12

1992: 1 trials (Observational 1) 1995: 1 trials (Observational 1) 2000: 2 trials (Observational 1, Not applicable 1) 2002: 1 trials (Phase 3 1) 2004: 1 trials (Observational 1) 2005: 1 trials (Phase 1 1) 2006: 1 trials (Phase 3 1) 2007: 3 trials (Phase 2 1, Phase 1/2 1, Phase 1 1) 2008: 5 trials (Phase 4 1, Phase 2 1, Phase 1/2 1, Phase 1 2) 2009: 5 trials (Observational 2, Phase 2 2, Phase 1/2 1) 2010: 4 trials (Observational 2, Not applicable 1, Phase 1/2 1) 2011: 6 trials (Observational 1, Phase 4 1, Phase 2 1, Phase 1/2 3) 2012: 5 trials (Observational 1, Not applicable 3, Phase 2 1) 2013: 4 trials (Observational 2, Phase 2 1, Phase 1/2 1) 2014: 5 trials (Observational 2, Phase 2 1, Phase 1/2 1, Phase 1 1) 2015: 2 trials (Observational 1, Phase 1 1) 2016: 2 trials (Observational 1, Phase 2 1) 2017: 2 trials (Observational 1, Phase 2 1) 2018: 4 trials (Observational 1, Not applicable 1, Phase 1/2 1, Phase 1 1) 2019: 6 trials (Observational 2, Phase 3 1, Phase 2 3) 2020: 12 trials (Observational 3, Not applicable 2, Phase 2 5, Phase 1 2) 2021: 4 trials (Observational 2, Phase 2 1, Phase 1/2 1) 2022: 3 trials (Observational 3) 2023: 1 trials (Not applicable 1) 2024: 3 trials (Observational 1, Phase 2 1, Phase 1/2 1) 2025: 4 trials (Observational 1, Not applicable 1, Phase 2 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 4
2025 4
2024 3
2023 1
2022 3
2021 4
2020 12
2019 6
2018 4
2017 2

No forecast is made for this condition: it averages 3.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 34 months across 66 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Lymphopenia trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 9
Phase 1/2 12
Phase 2 24
Phase 3 4
Phase 4 2
Not applicable 10
Observational 31
Expanded access 1

How many Lymphopenia trials are recruiting? (10)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 2
Recruiting 10
Enrolling by invitation 2
Active, not recruiting 6
Available 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Lymphopenia trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Institute of Allergy and Infectious Diseases (NIAID) 7
Revimmune 6
ImmunityBio, Inc. 4
National Human Genome Research Institute (NHGRI) 3

Which drugs are being tested for Lymphopenia? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
CYT107 10
N-803 4
Cytoxan 4
Melphalan 3

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
SQ Fludarabine 5
Peripheral blood stem cell transplantation 4
HD- Methotrexate (MTX) 3
Total Body Irradiation 3
Globulin, Immune 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Lymphopenia trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pyrexia 6 3
Hypoxia: Decreased O2 sat requiring support 4 1
Graft versus host disease 3 1
Acute graft versus host disease in intestine 2 1
Anaphylaxis reaction (rATG) 2 1

Which publications cover Lymphopenia? (222)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

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