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Condition (MeSH)

Mandibular Fractures

ClinicalTrials.gov lists 78 trials for Mandibular Fractures or a narrower condition beneath it. Stryker Craniomaxillofacial has the most among industry and government lead sponsors, with 3.

MeSH D008337 Nervous System Diseases C10 C26
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Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 4 Not applicable Not applicable 50 Observational Observational 18 Expanded access Expanded access 1 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 4 Not applicable Not applicable 50 Observational Observational 18 Expanded access Expanded access 1

Trials per phase (log scale)

78 of the 78 trials are tagged with Mandibular Fractures itself; the rest are tagged with a narrower condition beneath it.

Get the Mandibular Fractures report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Mandibular Fractures trials start? (17)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Expanded access

Top of scale: 16

2006: 1 trials (Phase 4 1) 2008: 1 trials (Expanded access 1) 2010: 1 trials (Phase 3 1) 2013: 1 trials (Not applicable 1) 2014: 4 trials (Observational 1, Not applicable 2, Phase 3 1) 2015: 2 trials (Not applicable 2) 2016: 1 trials (Not applicable 1) 2017: 5 trials (Observational 2, Not applicable 3) 2018: 4 trials (Observational 2, Not applicable 2) 2019: 8 trials (Observational 2, Not applicable 6) 2020: 5 trials (Observational 2, Not applicable 2, Phase 2/3 1) 2021: 4 trials (Observational 2, Not applicable 2) 2022: 2 trials (Not applicable 2) 2023: 5 trials (Not applicable 4, Phase 4 1) 2024: 16 trials (Observational 5, Not applicable 8, Phase 4 2, Phase 3 1) 2025: 10 trials (Observational 1, Not applicable 9)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 8
2025 10
2024 16
2023 5
2022 2
2021 4
2020 5
2019 8
2018 4
2017 5

Forecast of the full-year count, planned starts included, not rows of this table: about 10 trials starting in 2026 and about 11 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 31 months from start to primary completion across 7 trials still running at the 2026-10-09 snapshot; registered median of 17 months across 41 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Mandibular Fractures trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 2 1
Phase 2/3 1
Phase 3 3
Phase 4 4
Not applicable 50
Observational 18
Expanded access 1

How many Mandibular Fractures trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 9
Recruiting 6
Enrolling by invitation 1
Active, not recruiting 4
Completed 36

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Mandibular Fractures trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Stryker Craniomaxillofacial 3
Instituto Mexicano del Seguro Social 2
Zimmer Biomet 2

Which drugs are being tested for Mandibular Fractures? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Vitamin C 1
METHYLPREDNISOLONE 1

Interventions as named in the registry (5)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Application of autologous mesenchymal stem cells 1
Different post-operative antibiotic regimens following surgical treatment of mandible fractures 1
Dexamethasone/Dexamethasone acetate 1
Amoxicillin + clavulanic acid 1
Bupivacain 25% (Erector Spinae Plane Block) 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Mandibular Fractures trials report? (1)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Postoperative Infection 2 1

Which publications cover Mandibular Fractures? (155)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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