Condition (MeSH)
Marfan Syndrome
ClinicalTrials.gov lists 61 trials for Marfan Syndrome or a narrower condition beneath it. Bayside Health has the most among industry and government lead sponsors, with 1.
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Trials per phase (log scale)
61 of the 61 trials are tagged with Marfan Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Marfan Syndrome trials start? (24)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 10
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 3 |
| 2025 | 3 |
| 2024 | 3 |
| 2023 | 10 |
| 2022 | 2 |
| 2021 | 5 |
| 2020 | 4 |
| 2018 | 2 |
| 2017 | 1 |
| 2016 | 1 |
Showing 10 of 24 earlier years.
No forecast is made for this condition: it averages 4.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 61 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Marfan Syndrome trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 3 |
| Phase 3 | 9 |
| Phase 4 | 1 |
| Not applicable | 14 |
| Observational | 34 |
How many Marfan Syndrome trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 3 |
| Recruiting | 9 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 3 |
| Completed | 31 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Marfan Syndrome trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Bayside Health | 1 |
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Low dose losartan | 7 |
| Atenolol Pill | 6 |
| SR verapamil | 1 |
| Control (placebo) group | 1 |
| Losartan and Atenolol or Propranolol | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Marfan Syndrome trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pneumothorax NOS | 8 | 1 |
| Pneumonia | 5 | 1 |
| Depression | 4 | 1 |
| Agitation | 3 | 1 |
| Chest pain | 3 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Marfan Syndrome? (121)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 121 publications.
Prevalence (18)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Marfan syndrome | Prevalence at birth | 1-5 / 10 000 | United Kingdom | GB | Exact |
| Marfan syndrome | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Unspecified |
| Marfan syndrome | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Exact |
| Marfan syndrome | Prevalence at birth | 1-5 / 10 000 | United Kingdom | GB | Unspecified |
| Marfan syndrome | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Exact |
Showing 5 of 18 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Marfan syndrome | 558 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Marfan syndrome | 558 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.