Condition (MeSH)
Meconium Aspiration Syndrome
ClinicalTrials.gov lists 25 trials for Meconium Aspiration Syndrome or a narrower condition beneath it. Lady Hardinge Medical College has the most among industry and government lead sponsors, with 4.
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Trials per phase
25 of the 25 trials are tagged with Meconium Aspiration Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Meconium Aspiration Syndrome trials start? (17)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 1 |
| 2023 | 1 |
| 2022 | 1 |
| 2021 | 1 |
| 2019 | 2 |
| 2017 | 1 |
| 2015 | 2 |
| 2013 | 1 |
| 2012 | 1 |
Showing 10 of 17 earlier years.
No forecast is made for this condition: it averages 1.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 25 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Meconium Aspiration Syndrome trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 5 |
| Phase 4 | 2 |
| Not applicable | 14 |
| Observational | 2 |
How many Meconium Aspiration Syndrome trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 1 |
| Active, not recruiting | 1 |
| Completed | 13 |
| Terminated | 4 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Meconium Aspiration Syndrome trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Lady Hardinge Medical College | 4 |
| NICHD Neonatal Research Network | 3 |
| Sir Takhtasinhji General Hospital | 1 |
Which drugs are being tested for Meconium Aspiration Syndrome? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| SILDENAFIL | 1 |
| Lucinactant | 1 |
| Bovine Lipid Extract Surfactant | 1 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Bovine surfactant | 2 |
| Inhaled Nitric Oxide (iNO) use | 2 |
| induction of labor | 1 |
| citrate of caffeine | 1 |
| Standard Care | 1 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Meconium Aspiration Syndrome trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pulmonary hypertension NOS | 21 | 1 |
| Hypoxia | 17 | 1 |
| Hypotension NOS | 13 | 1 |
| Drug withdrawal syndrome | 3 | 1 |
| Cardiac tamponade | 2 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Meconium Aspiration Syndrome? (33)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Remote patient monitoring for management of diabetes mellitus in pregnancy is associated with improved maternal and neonatal outcomes. | American journal of obstetrics and gynecology | 2023 | Yes |
| Meconium-stained amniotic fluid. | American journal of obstetrics and gynecology | 2023 | Yes |
| Intrapartum amnioinfusion reduces meconium aspiration syndrome and improves neonatal outcomes in patients with meconium-stained fluid: a systematic review and meta-analysis. | American journal of obstetrics and gynecology | 2023 | Yes |
| Meconium-stained amniotic fluid and neonatal morbidity in nulliparous patients with prolonged pregnancy. | Acta obstetricia et gynecologica Scandinavica | 2023 | Yes |
| Severity of intrapartum fever and neonatal outcomes. | American journal of obstetrics and gynecology | 2022 | Yes |
Showing 5 of 33 publications.
Prevalence (3)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Meconium aspiration syndrome | Point prevalence | 1-9 / 100 000 | Europe | Not stated | Unspecified |
| Meconium aspiration syndrome | Point prevalence | 1-9 / 100 000 | Europe | Not stated | Exact |
| Meconium aspiration syndrome | Point prevalence | 1-9 / 100 000 | Europe | Not stated | Exact |
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Meconium aspiration syndrome | 70588 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Meconium aspiration syndrome | 70588 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.