Condition (MeSH)
Morphine Dependence
ClinicalTrials.gov lists 4 trials for Morphine Dependence or a narrower condition beneath it. BioXcel Therapeutics Inc has the most among industry and government lead sponsors, with 1.
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Trials per phase
4 of the 4 trials are tagged with Morphine Dependence itself; the rest are tagged with a narrower condition beneath it.
When did Morphine Dependence trials start? (3)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1/2
- Phase 3
- Not applicable
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2021 | 1 |
| 2020 | 1 |
| 2001 | 2 |
No forecast is made for this condition: it averages 0.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 4 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Morphine Dependence trials in? (3)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 1 |
| Phase 3 | 2 |
| Not applicable | 1 |
How many Morphine Dependence trials are recruiting? (2)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Completed | 3 |
| Terminated | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Morphine Dependence trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| BioXcel Therapeutics Inc | 1 |
Which publications cover Morphine Dependence? (25)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Socialization Alleviates Burden of Oxidative-Stress in Hippocampus and Prefrontal Cortex in Morphine Addiction Period in Male Rats. | Current molecular pharmacology | 2018 | Yes |
| Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model. | Scientific reports | 2018 | Yes |
| AMPA receptor positive allosteric modulators attenuate morphine tolerance and dependence. | Neuropharmacology | 2018 | Yes |
| Ellagic acid enhances morphine analgesia and attenuates the development of morphine tolerance and dependence in mice. | European journal of pharmacology | 2014 | Yes |
| Inhibition of brain oxidative stress and inducible nitric oxide synthase expression by thymoquinone attenuates the development of morphine tolerance and dependence in mice. | European journal of pharmacology | 2013 | Yes |
Showing 5 of 25 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.
Not computed for conditions with fewer than 10 trials: drugs tested.