Condition (MeSH)
Muscle Cramp
ClinicalTrials.gov lists 58 trials for Muscle Cramp or a narrower condition beneath it.
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Trials per phase
58 of the 58 trials are tagged with Muscle Cramp itself; the rest are tagged with a narrower condition beneath it.
When did Muscle Cramp trials start? (24)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 6 |
| 2024 | 2 |
| 2023 | 2 |
| 2022 | 5 |
| 2021 | 3 |
| 2020 | 5 |
| 2019 | 2 |
| 2018 | 3 |
| 2017 | 3 |
Showing 10 of 24 earlier years.
No forecast is made for this condition: it averages 3.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Muscle Cramp trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 2 |
| Phase 2 | 6 |
| Phase 2/3 | 2 |
| Phase 3 | 4 |
| Phase 4 | 5 |
| Not applicable | 32 |
| Observational | 5 |
How many Muscle Cramp trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 3 |
| Recruiting | 2 |
| Active, not recruiting | 3 |
| Completed | 41 |
| Terminated | 5 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Muscle Cramp trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Flex Pharma, Inc. | 2 |
| National Institute of Mental Health (NIMH) | 2 |
Which drugs are being tested for Muscle Cramp? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| SIMVASTATIN | 2 |
Interventions as named in the registry (14)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| FLX-787-ODT | 2 |
| baclofen 2% | 2 |
| Vitamin E | 2 |
| high sodium diet | 1 |
| NaCl 0.9% NS | 1 |
Showing 5 of 14 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Muscle Cramp trials report? (3)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Diverticulitis with pericecal abscess | 1 | 1 |
| Respiratory distress due to RSV | 1 | 1 |
| hepatic encephalopathy | 1 | 1 |
Which publications cover Muscle Cramp? (83)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| The RELAX randomized controlled trial: Stretching versus meditation for nocturnal muscle cramps. | Liver international : official journal of the International Association for the Study of the Liver | 2024 | Yes |
| Pharmacological Treatment for Dialysis-Related Muscle Cramps: A Systematic Review. | Seminars in dialysis | 2024 | Yes |
| The Effect of Muscle Cramps During Hemodialysis on Quality of Life and Habitual Physical Activity. | Medicina (Kaunas, Lithuania) | 2024 | Yes |
| Effects of warm or cold compresses applied to the legs during hemodialysis on cramps, fatigue, and patient comfort: A placebo-controlled randomized trial. | Hemodialysis international. International Symposium on Home Hemodialysis | 2023 | Yes |
| Muscle Cramping in the Marathon: Dehydration and Electrolyte Depletion vs. Muscle Damage. | Journal of strength and conditioning research | 2022 | Yes |
Showing 5 of 83 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.