Condition (MeSH)
Nephrosis, Lipoid
ClinicalTrials.gov lists 75 trials for Nephrosis, Lipoid or a narrower condition beneath it.
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Trials per phase
75 of the 75 trials are tagged with Nephrosis, Lipoid itself; the rest are tagged with a narrower condition beneath it.
When did Nephrosis, Lipoid trials start? (22)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 7 |
| 2025 | 5 |
| 2024 | 7 |
| 2023 | 5 |
| 2022 | 7 |
| 2021 | 2 |
| 2020 | 4 |
| 2019 | 6 |
| 2018 | 4 |
| 2017 | 2 |
Showing 10 of 22 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 7 trials starting in 2026 and about 6 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. The 2026 forecast is below the 7 already registered with a 2026 start date: at the cutoff, 2 trials were already registered to start in October to December, more than the method's monthly average allows for, and the method does not use those planned starts.
Prediction, not a registry value: median of 36 months from start to primary completion across 7 trials still running at the 2026-10-09 snapshot; registered median of 43 months across 30 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Nephrosis, Lipoid trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 15 |
| Phase 2/3 | 4 |
| Phase 3 | 9 |
| Phase 4 | 8 |
| Not applicable | 9 |
| Observational | 28 |
How many Nephrosis, Lipoid trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 7 |
| Recruiting | 24 |
| Active, not recruiting | 3 |
| Completed | 26 |
| Terminated | 3 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Nephrosis, Lipoid trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Goldfinch Bio, Inc. | 2 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2 |
| Aldeyra Therapeutics, Inc. | 1 |
| Alexion Pharmaceuticals, Inc. | 1 |
| Astellas Pharma Korea, Inc. | 1 |
Which drugs are being tested for Nephrosis, Lipoid? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| RITUXIMAB | 6 |
| Prednisone | 6 |
| PREDNISOLONE | 4 |
| Obinutuzumab | 2 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| IR Tacrolimus | 3 |
| Sham device | 2 |
| Supportive care+Tacrolimus+Ripertamab | 1 |
| Adalimumab-US | 1 |
| data collection | 1 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Nephrosis, Lipoid trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Hospitalization due to anasarca | 10 | 1 |
| Hospitalization due to fever, concern for infection, or immunosuppression | 9 | 1 |
| Acute kidney injury | 4 | 1 |
| Hospitalization due to acute kidney injury | 4 | 1 |
| Generalised oedema | 3 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Nephrosis, Lipoid? (38)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Repetitive administration of rituximab can achieve and maintain clinical remission in patients with MCD or FSGS. | Scientific reports | 2023 | Yes |
| Telitacicept for minimal change disease. | The Kaohsiung journal of medical sciences | 2023 | Yes |
| Interventions for minimal change disease in adults with nephrotic syndrome. | The Cochrane database of systematic reviews | 2022 | Yes |
| Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology. | Journal of the American Society of Nephrology : JASN | 2022 | Yes |
| Long-Term Efficacy and Safety of Repeated Rituximab to Maintain Remission in Idiopathic Childhood Nephrotic Syndrome: An International Study. | Journal of the American Society of Nephrology : JASN | 2022 | Yes |
Showing 5 of 38 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.