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Condition (MeSH)

Nutrition Disorders

ClinicalTrials.gov lists 16,367 trials for Nutrition Disorders or a narrower condition beneath it. Novo Nordisk A/S has the most among industry and government lead sponsors, with 203.

MeSH D009748 Nutritional and Metabolic Diseases C18
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Phase 1 Phase 1 826 Phase 1/2 Phase 1/2 176 Phase 2 Phase 2 825 Phase 2/3 Phase 2/3 170 Phase 3 Phase 3 690 Phase 4 Phase 4 775 Not applicable Not applicable 9,367 Observational Observational 3,530 Phase 1 Phase 1 826 Phase 1/2 Phase 1/2 176 Phase 2 Phase 2 825 Phase 2/3 Phase 2/3 170 Phase 3 Phase 3 690 Phase 4 Phase 4 775 Not applicable Not applicable 9,367 Observational Observational 3,530

Trials per phase (log scale)

2 more sections with rows

224 of the 16,367 trials are tagged with Nutrition Disorders itself; the rest are tagged with a narrower condition beneath it.

Get the Nutrition Disorders report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Nutrition Disorders trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 39 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 1,026

1990: 3 trials (Observational 3) 1991: 5 trials (Observational 5) 1992: 4 trials (Observational 3, Phase 3 1) 1993: 5 trials (Observational 4, Phase 2 1) 1994: 4 trials (Observational 2, Phase 3 1, Phase 1/2 1) 1995: 13 trials (Observational 9, Not applicable 2, Phase 3 1, Phase 2 1) 1996: 8 trials (Observational 5, Not applicable 2, Phase 3 1) 1997: 10 trials (Observational 3, Not applicable 4, Phase 3 1, Phase 2 1, Phase 1/2 1) 1998: 23 trials (Observational 9, Not applicable 6, Phase 4 1, Phase 3 2, Phase 2 5) 1999: 37 trials (Observational 16, Not applicable 12, Phase 4 1, Phase 3 2, Phase 2/3 1, Phase 2 3, Phase 1/2 2) 2000: 45 trials (Observational 12, Not applicable 13, Phase 4 2, Phase 3 10, Phase 2 6, Phase 1 2) 2001: 60 trials (Observational 19, Not applicable 23, Phase 4 3, Phase 3 11, Phase 2 4) 2002: 70 trials (Observational 10, Not applicable 42, Phase 4 4, Phase 3 5, Phase 2/3 1, Phase 2 5, Phase 1/2 1, Phase 1 2) 2003: 104 trials (Observational 22, Not applicable 39, Phase 4 11, Phase 3 11, Phase 2/3 5, Phase 2 8, Phase 1/2 4, Phase 1 4) 2004: 196 trials (Observational 34, Not applicable 86, Phase 4 17, Phase 3 21, Phase 2/3 3, Phase 2 23, Phase 1/2 5, Phase 1 7) 2005: 238 trials (Observational 49, Not applicable 103, Phase 4 15, Phase 3 16, Phase 2/3 8, Phase 2 25, Phase 1/2 5, Phase 1 17) 2006: 306 trials (Observational 55, Not applicable 149, Phase 4 20, Phase 3 29, Phase 2/3 4, Phase 2 26, Phase 1/2 6, Phase 1 17) 2007: 389 trials (Observational 82, Not applicable 197, Phase 4 24, Phase 3 34, Phase 2/3 5, Phase 2 26, Phase 1/2 4, Phase 1 17) 2008: 468 trials (Observational 112, Not applicable 219, Phase 4 21, Phase 3 30, Phase 2/3 9, Phase 2 41, Phase 1/2 7, Phase 1 29) 2009: 533 trials (Observational 126, Not applicable 268, Phase 4 36, Phase 3 20, Phase 2/3 12, Phase 2 36, Phase 1/2 3, Phase 1 32) 2010: 570 trials (Observational 124, Not applicable 316, Phase 4 38, Phase 3 15, Phase 2/3 17, Phase 2 22, Phase 1/2 5, Phase 1 33) 2011: 611 trials (Observational 130, Not applicable 340, Phase 4 40, Phase 3 32, Phase 2/3 5, Phase 2 32, Phase 1/2 7, Phase 1 25) 2012: 667 trials (Observational 129, Not applicable 401, Phase 4 45, Phase 3 23, Phase 2/3 6, Phase 2 31, Phase 1/2 6, Phase 1 26) 2013: 624 trials (Observational 120, Not applicable 366, Phase 4 40, Phase 3 22, Phase 2/3 5, Phase 2 29, Phase 1/2 13, Phase 1 29) 2014: 674 trials (Observational 129, Not applicable 419, Phase 4 42, Phase 3 17, Phase 2/3 11, Phase 2 20, Phase 1/2 8, Phase 1 28) 2015: 732 trials (Observational 146, Not applicable 481, Phase 4 34, Phase 3 14, Phase 2/3 4, Phase 2 29, Phase 1/2 6, Phase 1 18) 2016: 845 trials (Other 1, Observational 212, Not applicable 498, Phase 4 37, Phase 3 24, Phase 2/3 10, Phase 2 27, Phase 1/2 5, Phase 1 31) 2017: 809 trials (Other 1, Observational 161, Not applicable 515, Phase 4 42, Phase 3 17, Phase 2/3 8, Phase 2 35, Phase 1/2 8, Phase 1 22) 2018: 862 trials (Observational 182, Not applicable 548, Phase 4 29, Phase 3 26, Phase 2/3 5, Phase 2 30, Phase 1/2 9, Phase 1 33) 2019: 862 trials (Observational 205, Not applicable 545, Phase 4 37, Phase 3 21, Phase 2/3 7, Phase 2 13, Phase 1/2 5, Phase 1 29) 2020: 703 trials (Other 1, Observational 190, Not applicable 410, Phase 4 25, Phase 3 12, Phase 2/3 3, Phase 2 20, Phase 1/2 7, Phase 1 35) 2021: 847 trials (Observational 181, Not applicable 536, Phase 4 25, Phase 3 30, Phase 2/3 8, Phase 2 38, Phase 1/2 5, Phase 1 24) 2022: 916 trials (Observational 232, Not applicable 553, Phase 4 25, Phase 3 23, Phase 2/3 15, Phase 2 27, Phase 1/2 5, Phase 1 36) 2023: 997 trials (Observational 191, Not applicable 632, Phase 4 36, Phase 3 37, Phase 2/3 7, Phase 2 40, Phase 1/2 13, Phase 1 41) 2024: 1,005 trials (Observational 208, Not applicable 571, Phase 4 30, Phase 3 35, Phase 2/3 5, Phase 2 58, Phase 1/2 15, Phase 1 83) 2025: 1,026 trials (Observational 194, Not applicable 551, Phase 4 42, Phase 3 53, Phase 2/3 4, Phase 2 76, Phase 1/2 13, Phase 1 93)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 961
2025 1,026
2024 1,005
2023 997
2022 916
2021 847
2020 703
2019 862
2018 862
2017 809

Forecast of the full-year count, planned starts included, not rows of this table: about 1,200 trials starting in 2026 and about 1,000 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 1,411 trials still running at the 2026-10-09 snapshot; registered median of 19 months across 10,917 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Nutrition Disorders trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 826
Phase 1/2 176
Phase 2 825
Phase 2/3 170
Phase 3 690
Phase 4 775
Not applicable 9,367
Observational 3,530
Expanded access 5
Unknown 3

How many Nutrition Disorders trials are recruiting? (12)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 667
Recruiting 1,576
Enrolling by invitation 132
Active, not recruiting 682
Available 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Nutrition Disorders trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Novo Nordisk A/S 203
Eli Lilly and Company 112
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 112

Which drugs are being tested for Nutrition Disorders? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Semaglutide 178
Calcium/Vitamin D 168
TIRZEPATIDE 131
Calcium-vitamin D3 119
LIRAGLUTIDE 102

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Exercise 159
CHOLECALCIFEROL 114
1% Metformin 109
Control (placebo) group 86
Diet 84

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Nutrition Disorders trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Major Adverse Cardiovascular Events 6,762 1
Major Adverse Kidney Events 5,557 1
Any SAE Report 2,676 1
Acute myocardial infarction 993 37
Atrial fibrillation 938 50

Which publications cover Nutrition Disorders? (316)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (6)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages