Condition (MeSH)
Otitis Media with Effusion
ClinicalTrials.gov lists 78 trials for Otitis Media with Effusion or a narrower condition beneath it. Vastra Gotaland Region has the most among industry and government lead sponsors, with 3.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
78 of the 78 trials are tagged with Otitis Media with Effusion itself; the rest are tagged with a narrower condition beneath it.
When did Otitis Media with Effusion trials start? (26)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 6 |
| 2025 | 5 |
| 2024 | 5 |
| 2023 | 1 |
| 2022 | 6 |
| 2021 | 1 |
| 2020 | 3 |
| 2019 | 3 |
| 2018 | 5 |
| 2017 | 7 |
Showing 10 of 26 earlier years.
No forecast is made for this condition: it averages 4.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 20 months across 41 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Otitis Media with Effusion trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 2/3 | 2 |
| Phase 3 | 10 |
| Phase 4 | 4 |
| Not applicable | 37 |
| Observational | 22 |
How many Otitis Media with Effusion trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 7 |
| Recruiting | 6 |
| Active, not recruiting | 1 |
| Completed | 42 |
| Terminated | 1 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Otitis Media with Effusion trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Vastra Gotaland Region | 3 |
| Integra LifeSciences Corporation | 2 |
| Otonomy, Inc. | 2 |
| PhotoniCare, Inc. | 2 |
| Tusker Medical | 2 |
Showing 5 of 6 sponsors.
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Mometasone furoate as a nasal spray | 2 |
| OTO-201 | 2 |
| lansoprazole OD | 2 |
| Acupuncture | 1 |
| Steroid Drug | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Otitis Media with Effusion trials report? (8)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Respiratory Syncytial Virus Infection | 3 | 1 |
| Bronchiolitis | 2 | 1 |
| Pneumonia | 2 | 1 |
| Constipation | 1 | 1 |
| Gastroenteritis | 1 | 1 |
Showing 5 of 8 adverse events.
Which publications cover Otitis Media with Effusion? (113)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Microplastic presence in the fluid of otitis media with effusion. | International journal of pediatric otorhinolaryngology | 2025 | Yes |
| Observation or Otolaryngology Surveillance After Ventilation Tube Insertion in Children: The ConVenTu Noninferiority Randomized Clinical Trial. | JAMA otolaryngology-- head & neck surgery | 2025 | Yes |
| Topical and oral steroids for otitis media with effusion (OME) in children. | The Cochrane database of systematic reviews | 2023 | Yes |
| Ventilation tubes (grommets) for otitis media with effusion (OME) in children. | The Cochrane database of systematic reviews | 2023 | Yes |
| Diagnostic Accuracy of Group A Streptococcus Rapid Antigen Detection Test on Middle Ear Fluid in Children With Acute Otitis Media With Spontaneous Perforation: A Prospective Multicenter Evaluation. | The Pediatric infectious disease journal | 2023 | Yes |
Showing 5 of 113 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.