Condition (MeSH)
Persistent Fetal Circulation Syndrome
ClinicalTrials.gov lists 40 trials for Persistent Fetal Circulation Syndrome or a narrower condition beneath it. NICHD Neonatal Research Network has the most among industry and government lead sponsors, with 5.
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Trials per phase
40 of the 40 trials are tagged with Persistent Fetal Circulation Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Persistent Fetal Circulation Syndrome trials start? (22)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 4 |
| 2024 | 1 |
| 2023 | 1 |
| 2021 | 4 |
| 2020 | 2 |
| 2017 | 2 |
| 2016 | 2 |
| 2015 | 2 |
| 2013 | 2 |
Showing 10 of 22 earlier years.
No forecast is made for this condition: it averages 1.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Persistent Fetal Circulation Syndrome trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 1/2 | 3 |
| Phase 2 | 5 |
| Phase 3 | 5 |
| Phase 4 | 4 |
| Not applicable | 8 |
| Observational | 14 |
How many Persistent Fetal Circulation Syndrome trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 5 |
| Active, not recruiting | 1 |
| Completed | 15 |
| Terminated | 8 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Persistent Fetal Circulation Syndrome trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| NICHD Neonatal Research Network | 5 |
| Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 3 |
| National Heart, Lung, and Blood Institute (NHLBI) | 2 |
| Actelion | 1 |
| Ferrer Internacional S.A. | 1 |
Showing 5 of 6 sponsors.
Which drugs are being tested for Persistent Fetal Circulation Syndrome? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| SILDENAFIL | 8 |
| BOSENTAN | 2 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Inhaled Nitric Oxide (iNO) use | 4 |
| Inhaled Milrinone | 3 |
| Standard iNO therapy | 1 |
| Nebulized nitroglycerine as adjunctive therapy | 1 |
| NO inhalation | 1 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Persistent Fetal Circulation Syndrome trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Neonatal respiratory failure | 6 | 1 |
| Respiratory syncytial virus infection | 5 | 1 |
| Fatal | 3 | 1 |
| Respiratory failure | 3 | 2 |
| Shock | 3 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Persistent Fetal Circulation Syndrome? (59)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 59 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.