Condition (MeSH)
Phantom Limb
ClinicalTrials.gov lists 159 trials for Phantom Limb or a narrower condition beneath it. VA Office of Research and Development has the most among industry and government lead sponsors, with 4.
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Trials per phase (log scale)
159 of the 159 trials are tagged with Phantom Limb itself; the rest are tagged with a narrower condition beneath it.
When did Phantom Limb trials start? (25)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
- Unknown
Top of scale: 16
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 12 |
| 2025 | 4 |
| 2024 | 13 |
| 2023 | 13 |
| 2022 | 16 |
| 2021 | 14 |
| 2020 | 4 |
| 2019 | 3 |
| 2018 | 6 |
| 2017 | 14 |
Showing 10 of 25 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 12 trials starting in 2026 and about 8 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 30 months from start to primary completion across 16 trials still running at the 2026-10-09 snapshot; registered median of 26 months across 85 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Phantom Limb trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 4 |
| Phase 2/3 | 2 |
| Phase 3 | 7 |
| Phase 4 | 8 |
| Not applicable | 103 |
| Observational | 28 |
| Unknown | 1 |
How many Phantom Limb trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 8 |
| Recruiting | 23 |
| Enrolling by invitation | 3 |
| Active, not recruiting | 3 |
| Completed | 70 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Phantom Limb trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| VA Office of Research and Development | 4 |
| Apurano Pharmaceuticals GmbH | 2 |
| Integrum | 2 |
Which drugs are being tested for Phantom Limb? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Pregabalin | 2 |
Interventions as named in the registry (14)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Acupuncture | 3 |
| L:Lidocaine | 3 |
| Adezunap | 2 |
| Transcranial Magnetic Stimulation | 2 |
| type A botulinum toxin | 2 |
Showing 5 of 14 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Phantom Limb trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Surgical and medical procedures | 15 | 1 |
| Infections and infestations | 11 | 1 |
| General Disorder | 9 | 1 |
| Medical device discomfort | 5 | 1 |
| Postoperative wound infection | 5 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Phantom Limb? (243)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Graded Motor Imagery (GRAMI Protocol) for Phantom Limb Pain: A Randomised Clinical Trial of Home-Based Intervention. | European journal of pain (London, England) | 2026 | Yes |
| Extended reality used in the treatment of phantom limb pain: a multicenter, double-blind, randomized controlled trial. | Pain | 2025 | Yes |
| Phantom Limb Pain Management. | The Journal of hand surgery | 2025 | Yes |
| The missing link: How is the phantom limb influenced by prosthesis wearing in people with lower-limb amputation? | Prosthetics and orthotics international | 2025 | Yes |
| Treating Lower Phantom Limb Pain in the Postoperative Acute Care Setting Using Virtual Reality: Protocol for a 4-Phase Development and Feasibility Trial. | JMIR research protocols | 2025 | Yes |
Showing 5 of 243 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.