Condition (MeSH)
Proctitis
ClinicalTrials.gov lists 21 trials for Proctitis or a narrower condition beneath it. Bausch Health Americas, Inc. has the most among industry and government lead sponsors, with 3.
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Trials per phase
13 of the 21 trials are tagged with Proctitis itself; the rest are tagged with a narrower condition beneath it.
When did Proctitis trials start? (12)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2024 | 2 |
| 2022 | 1 |
| 2021 | 1 |
| 2020 | 1 |
| 2015 | 2 |
| 2014 | 1 |
| 2013 | 2 |
| 2012 | 2 |
| 2011 | 1 |
| 2010 | 4 |
Showing 10 of 12 earlier years.
No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 21 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Proctitis trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 3 |
| Phase 2/3 | 1 |
| Phase 3 | 6 |
| Phase 4 | 1 |
| Not applicable | 3 |
| Observational | 7 |
How many Proctitis trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Active, not recruiting | 1 |
| Completed | 13 |
| Terminated | 4 |
| Withdrawn | 1 |
| Unknown status | 2 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Proctitis trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Bausch Health Americas, Inc. | 3 |
| Dr. Falk Pharma GmbH | 1 |
| Forest Laboratories | 1 |
| NHS Grampian | 1 |
| PurGenesis Technologies Inc. | 1 |
Which drugs are being tested for Proctitis? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Maltodextrin | 1 |
| Aloe Vera Gel | 1 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Budesonide EC | 3 |
| MMX Mesalamine | 2 |
| Hyperbaric Oxygen | 1 |
| Budesonide 4 mg suppository | 1 |
| Symbiotic | 1 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Proctitis trials report? (9)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Colitis ulcerative | 2 | 2 |
| Abdominal pain | 1 | 1 |
| Acute generalised exanthematous pustulosis | 1 | 1 |
| Anaemia | 1 | 1 |
| Arterial thrombosis limb | 1 | 1 |
Showing 5 of 9 adverse events.
Which publications cover Proctitis? (93)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Efficacy and Safety of Etrasimod in Patients with Moderately to Severely Active Isolated Proctitis: Results From the Phase 3 ELEVATE UC Clinical Programme. | Journal of Crohn's & colitis | 2024 | Yes |
| Circulating microvesicles correlate with radiation proctitis complication after radiotherapy. | Scientific reports | 2023 | Yes |
| Comparative efficacy of oral drugs for chronic radiation proctitis - a systematic review. | Systematic reviews | 2023 | Yes |
| Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study. | Lancet (London, England) | 2022 | Yes |
| Prevention of acute radiation-induced Proctitis by Aloe vera: a prospective randomized, double-blind, placebo controlled clinical trial in Pelvic Cancer patients. | BMC complementary medicine and therapies | 2020 | Yes |
Showing 5 of 93 publications.
Sub-conditions in MeSH (1)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.