Condition (MeSH)
Pulmonary Eosinophilia
ClinicalTrials.gov lists 103 trials for Pulmonary Eosinophilia or a narrower condition beneath it. AstraZeneca has the most among industry and government lead sponsors, with 17.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
103 of the 103 trials are tagged with Pulmonary Eosinophilia itself; the rest are tagged with a narrower condition beneath it.
When did Pulmonary Eosinophilia trials start? (18)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 13
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 5 |
| 2025 | 5 |
| 2024 | 8 |
| 2023 | 11 |
| 2022 | 10 |
| 2021 | 13 |
| 2020 | 13 |
| 2019 | 8 |
| 2018 | 5 |
| 2017 | 7 |
Showing 10 of 18 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 4 trials starting in 2026 and about 5 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. The 2026 forecast is below the 5 already registered with a 2026 start date: at the cutoff, 2 trials were already registered to start in October to December, more than the method's monthly average allows for, and the method does not use those planned starts.
Prediction, not a registry value: median of 36 months from start to primary completion across 14 trials still running at the 2026-10-09 snapshot; registered median of 21 months across 61 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Pulmonary Eosinophilia trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 1 |
| Phase 2 | 9 |
| Phase 3 | 21 |
| Phase 4 | 18 |
| Not applicable | 5 |
| Observational | 47 |
How many Pulmonary Eosinophilia trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 7 |
| Recruiting | 9 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 8 |
| Completed | 49 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Pulmonary Eosinophilia trials? (8)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| AstraZeneca | 17 |
| GlaxoSmithKline | 9 |
| Teva Branded Pharmaceutical Products R&D, Inc. | 5 |
| Areteia Therapeutics | 4 |
| Advagene Biopharma Co. Ltd. | 2 |
Showing 5 of 8 sponsors.
Which drugs are being tested for Pulmonary Eosinophilia? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Reslizumab | 6 |
| Dexpramipexole | 5 |
| Depemokimab | 2 |
| SOC | 2 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Mepolizumab SC | 20 |
| Benralizumab Arm B | 13 |
| AD17002 | 2 |
| Dupilumab/Dupixent | 2 |
| Mepolizumab 100 MG Injection [Nucala] | 2 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Pulmonary Eosinophilia trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Asthma | 155 | 16 |
| Pneumonia | 24 | 9 |
| Lower respiratory tract infection | 9 | 6 |
| Nasal polyps | 8 | 4 |
| Sinusitis | 8 | 7 |
Showing 5 of 10 adverse events.
Which publications cover Pulmonary Eosinophilia? (78)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Prospective direct comparison of biologic treatments for severe eosinophilic asthma: Findings from the PRISM study. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology | 2024 | Yes |
| Reduction of daily maintenance inhaled corticosteroids in patients with severe eosinophilic asthma treated with benralizumab (SHAMAL): a randomised, multicentre, open-label, phase 4 study. | Lancet (London, England) | 2024 | Yes |
| CT Mucus Score and <sup>129</sup>Xe MRI Ventilation Defects After 2.5 Years' Anti-IL-5Rα in Eosinophilic Asthma. | Chest | 2023 | Yes |
| Sputum Type 2 Markers Could Predict Remission in Severe Asthma Treated With Anti-IL-5. | Chest | 2023 | Yes |
| The effects of benralizumab on airway geometry and dynamics in severe eosinophilic asthma: a single-arm study design exploring a functional respiratory imaging approach. | Respiratory research | 2023 | Yes |
Showing 5 of 78 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.