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Condition (MeSH)

Chronic Kidney Disease-Mineral and Bone Disorder

ClinicalTrials.gov lists 73 trials for Chronic Kidney Disease-Mineral and Bone Disorder or a narrower condition beneath it.

MeSH D012080 Musculoskeletal Diseases C05 C12 C18 C19 C23
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Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 12 Phase 3 Phase 3 3 Phase 4 Phase 4 9 Not applicable Not applicable 11 Observational Observational 36 Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 12 Phase 3 Phase 3 3 Phase 4 Phase 4 9 Not applicable Not applicable 11 Observational Observational 36

Trials per phase (log scale)

73 of the 73 trials are tagged with Chronic Kidney Disease-Mineral and Bone Disorder itself; the rest are tagged with a narrower condition beneath it.

Get the Chronic Kidney Disease-Mineral and Bone Disorder report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Chronic Kidney Disease-Mineral and Bone Disorder trials start? (23)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 7

1995: 1 trials (Phase 2 1) 2000: 1 trials (Phase 2 1) 2001: 1 trials (Phase 2 1) 2002: 1 trials (Phase 4 1) 2005: 1 trials (Observational 1) 2006: 7 trials (Observational 3, Not applicable 2, Phase 1/2 1, Phase 1 1) 2007: 1 trials (Not applicable 1) 2008: 1 trials (Observational 1) 2009: 2 trials (Observational 1, Phase 3 1) 2011: 4 trials (Observational 2, Phase 3 1, Phase 2 1) 2012: 5 trials (Observational 1, Phase 4 2, Phase 2 2) 2015: 4 trials (Observational 3, Not applicable 1) 2016: 4 trials (Observational 3, Phase 2 1) 2017: 2 trials (Observational 1, Phase 4 1) 2018: 5 trials (Observational 3, Phase 4 1, Phase 2 1) 2019: 2 trials (Observational 2) 2020: 5 trials (Observational 3, Not applicable 1, Phase 2 1) 2021: 4 trials (Observational 2, Phase 4 1, Phase 3 1) 2022: 7 trials (Observational 4, Not applicable 1, Phase 4 2) 2023: 3 trials (Observational 1, Not applicable 1, Phase 4 1) 2024: 1 trials (Phase 2 1) 2025: 6 trials (Observational 2, Not applicable 3, Phase 2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 5
2025 6
2024 1
2023 3
2022 7
2021 4
2020 5
2019 2
2018 5
2017 2

No forecast is made for this condition: it averages 4.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 23 months across 33 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Chronic Kidney Disease-Mineral and Bone Disorder trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 1/2 1
Phase 2 12
Phase 3 3
Phase 4 9
Not applicable 11
Observational 36

How many Chronic Kidney Disease-Mineral and Bone Disorder trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 2
Recruiting 13
Enrolling by invitation 1
Active, not recruiting 4
Completed 33

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Chronic Kidney Disease-Mineral and Bone Disorder trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
KAI Pharmaceuticals 2
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2
AbbVie (prior sponsor, Abbott) 1
Amgen 1

Which drugs are being tested for Chronic Kidney Disease-Mineral and Bone Disorder? (6)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Etelcalcetide 3
Sevelamer 2
Calcitriol 2
Antacid 2
Cinacalcet 2

Interventions as named in the registry (9)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
CHOLECALCIFEROL 3
Paricalitol 2
Lanthanum Carbonate (Fosrenol, BAY77-1931) Granule 2
Transdermal Teriparatide 2
Nicotinamide 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Chronic Kidney Disease-Mineral and Bone Disorder trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
In patient 9 1
Pneumonia 6 3
AMI 5 1
Stroke 5 1
congestive heart failure 4 1

Which publications cover Chronic Kidney Disease-Mineral and Bone Disorder? (62)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD). The Cochrane database of systematic reviews 2025 Yes
Recommended calcium intake in adults and children with chronic kidney disease-a European consensus statement. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2024 Yes
Parathyroidectomy versus oral cinacalcet on cardiovascular parameters in peritoneal dialysis patients with advanced secondary hyperparathyroidism (PROCEED): a randomized trial. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2023 Yes
FGF-23 and sclerostin in serum and bone of CKD patients. Clinical nephrology 2023 Yes
Association between CKD-MBD and mortality in older patients with advanced CKD-results from the EQUAL study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2023 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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