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Condition (MeSH)

Rift Valley Fever

ClinicalTrials.gov lists 11 trials for Rift Valley Fever or a narrower condition beneath it. U.S. Army Medical Research and Development Command has the most among industry and government lead sponsors, with 4.

MeSH D012295 Infections C01 C06 C22 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 3 Phase 2 Phase 2 5 Observational Observational 3 Phase 1 Phase 1 3 Phase 2 Phase 2 5 Observational Observational 3

Trials per phase

11 of the 11 trials are tagged with Rift Valley Fever itself; the rest are tagged with a narrower condition beneath it.

Get the Rift Valley Fever report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Rift Valley Fever trials start? (7)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Observational

Top of scale: 4

2004: 1 trials (Phase 2 1) 2006: 2 trials (Observational 1, Phase 2 1) 2009: 1 trials (Phase 2 1) 2018: 1 trials (Phase 2 1) 2021: 1 trials (Phase 1 1) 2022: 1 trials (Phase 1 1) 2025: 4 trials (Observational 2, Phase 2 1, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2025 4
2022 1
2021 1
2018 1
2009 1
2006 2
2004 1

No forecast is made for this condition: it averages 1.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Rift Valley Fever trials in? (3)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 3
Phase 2 5
Observational 3

How many Rift Valley Fever trials are recruiting? (3)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 3
Active, not recruiting 2
Completed 6

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Rift Valley Fever trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
U.S. Army Medical Research and Development Command 4
IDBiologics, Inc. 1
National Institute of Allergy and Infectious Diseases (NIAID) 1

Which drugs are being tested for Rift Valley Fever? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Rabies Vaccine 1

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
ChAdOx1 RVF 3
IDB-011 dose level 3 1
IDB-011 dose level 5 1
TSI-GSD 200 RVF Vaccine 1
Inactivated, Dried (TSI-GSD 200), RVF Vaccine 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Rift Valley Fever trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Atrial fibrillation 1 1
Back surgery 1 1
Cyst exicision 1 1
Laproscopic surgery for RLQ pain 1 1
Left nephrectomy 1 1

Which publications cover Rift Valley Fever? (3)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Safety and immunogenicity of a ChAdOx1 vaccine against Rift Valley fever in UK adults: an open-label, non-randomised, first-in-human phase 1 clinical trial. The Lancet. Infectious diseases 2023 Yes
Global risk mapping for major diseases transmitted by Aedes aegypti and Aedes albopictus. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2018 No
Potential application of silver nanoparticles to control the infectivity of Rift Valley fever virus in vitro and in vivo. Nanomedicine : nanotechnology, biology, and medicine 2016 No

Prevalence (3)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Rift valley fever Annual incidence <1 / 1 000 000 Europe Not stated Exact
Rift valley fever Annual incidence <1 / 1 000 000 Europe Not stated Exact
Rift valley fever Annual incidence <1 / 1 000 000 Europe Not stated Unspecified

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Rift valley fever 319251 Exact Orphadata Science knowledge files, Product 1
Rift valley fever 319251 Exact Orphanet Rare Disease Ontology (ORDO)

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

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