Condition (MeSH)
Rosacea
ClinicalTrials.gov lists 222 trials for Rosacea or a narrower condition beneath it. Galderma R&D has the most among industry and government lead sponsors, with 24.
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Trials per phase (log scale)
222 of the 222 trials are tagged with Rosacea itself; the rest are tagged with a narrower condition beneath it.
When did Rosacea trials start? (24)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 19
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 6 |
| 2025 | 10 |
| 2024 | 14 |
| 2023 | 13 |
| 2022 | 10 |
| 2021 | 10 |
| 2020 | 6 |
| 2019 | 9 |
| 2018 | 14 |
| 2017 | 19 |
Showing 10 of 24 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 8 trials starting in 2026 and about 10 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 28 months from start to primary completion across 14 trials still running at the 2026-10-09 snapshot; registered median of 10 months across 172 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Rosacea trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 24 |
| Phase 1/2 | 7 |
| Phase 2 | 47 |
| Phase 2/3 | 2 |
| Phase 3 | 36 |
| Phase 4 | 27 |
| Not applicable | 56 |
| Observational | 23 |
How many Rosacea trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 13 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 2 |
| Completed | 167 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Rosacea trials? (12)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Galderma R&D | 24 |
| LEO Pharma | 8 |
| Allergan | 7 |
| Maruho Co., Ltd. | 5 |
| Sol-Gel Technologies, Ltd. | 5 |
Showing 5 of 12 sponsors.
Which drugs are being tested for Rosacea? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Azelaic Acid | 10 |
| Ivermectin | 6 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Doxycline | 13 |
| Vehicle Foam | 5 |
| Ivermectin 1% cream | 4 |
| Azelaic Acid foam 15% | 4 |
| S5G4T-1 | 3 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Rosacea trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Atrial fibrillation | 10 | 4 |
| Basal cell carcinoma | 8 | 3 |
| Pneumonia | 8 | 7 |
| Transient ischaemic attack | 8 | 2 |
| Angina pectoris | 6 | 3 |
Showing 5 of 10 adverse events.
Which publications cover Rosacea? (122)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Efficacy and safety of tranilast combined with minocycline in the treatment of moderate-to-severe rosacea: a prospective, randomized controlled study. | The Journal of dermatological treatment | 2026 | Yes |
| Efficacy, Safety, and Tolerability of Oral DFD-29, a Low-Dose Formulation of Minocycline, in Rosacea: Two Phase 3 Randomized Clinical Trials. | JAMA dermatology | 2025 | Yes |
| Elevated plasma levels of calcitonin gene-related peptide in individuals with rosacea: A cross-sectional case-control study. | Journal of the European Academy of Dermatology and Venereology : JEADV | 2025 | Yes |
| Low-Energy Delicate Pulsed Light Therapy for Sensitive Skin: A Retrospective Study. | Journal of cosmetic dermatology | 2025 | Yes |
| Efficacy and safety comparison between pulsed dye laser and intense pulsed light configured with different wavelength bands in treating erythematotelangiectatic rosacea. | Lasers in medical science | 2024 | Yes |
Showing 5 of 122 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.