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Condition (MeSH)

Skin Diseases

ClinicalTrials.gov lists 31,655 trials for Skin Diseases or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 519.

MeSH D012871 Skin and Connective Tissue Diseases C17
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Phase 1 Phase 1 3,680 Phase 1/2 Phase 1/2 1,607 Phase 2 Phase 2 6,287 Phase 2/3 Phase 2/3 398 Phase 3 Phase 3 3,136 Phase 4 Phase 4 1,496 Not applicable Not applicable 8,497 Observational Observational 6,471 Phase 1 Phase 1 3,680 Phase 1/2 Phase 1/2 1,607 Phase 2 Phase 2 6,287 Phase 2/3 Phase 2/3 398 Phase 3 Phase 3 3,136 Phase 4 Phase 4 1,496 Not applicable Not applicable 8,497 Observational Observational 6,471

Trials per phase (log scale)

2 more sections with rows

495 of the 31,655 trials are tagged with Skin Diseases itself; the rest are tagged with a narrower condition beneath it.

Get the Skin Diseases report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Skin Diseases trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 62 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access, Unknown)

Top of scale: 1,951

1990: 11 trials (Observational 4, Not applicable 1, Phase 4 1, Phase 3 2, Phase 2 2, Phase 1/2 1) 1991: 18 trials (Observational 6, Not applicable 2, Phase 3 2, Phase 2/3 1, Phase 2 4, Phase 1/2 1, Phase 1 2) 1992: 18 trials (Observational 5, Not applicable 3, Phase 3 5, Phase 2 3, Phase 1 2) 1993: 20 trials (Observational 3, Not applicable 1, Phase 3 13, Phase 2 1, Phase 1/2 1, Phase 1 1) 1994: 29 trials (Observational 7, Not applicable 2, Phase 3 7, Phase 2 7, Phase 1/2 2, Phase 1 4) 1995: 46 trials (Observational 12, Not applicable 1, Phase 3 12, Phase 2/3 1, Phase 2 10, Phase 1/2 4, Phase 1 6) 1996: 78 trials (Observational 18, Not applicable 3, Phase 4 2, Phase 3 26, Phase 2 14, Phase 1/2 3, Phase 1 12) 1997: 96 trials (Observational 15, Not applicable 9, Phase 4 2, Phase 3 18, Phase 2/3 1, Phase 2 28, Phase 1/2 12, Phase 1 11) 1998: 117 trials (Observational 18, Not applicable 9, Phase 3 28, Phase 2/3 2, Phase 2 42, Phase 1/2 6, Phase 1 12) 1999: 154 trials (Observational 23, Not applicable 7, Phase 4 2, Phase 3 34, Phase 2/3 2, Phase 2 49, Phase 1/2 9, Phase 1 28) 2000: 221 trials (Observational 37, Not applicable 26, Phase 4 8, Phase 3 30, Phase 2/3 4, Phase 2 71, Phase 1/2 20, Phase 1 25) 2001: 224 trials (Observational 29, Not applicable 18, Phase 4 12, Phase 3 47, Phase 2/3 3, Phase 2 69, Phase 1/2 15, Phase 1 31) 2002: 293 trials (Observational 32, Not applicable 30, Phase 4 19, Phase 3 62, Phase 2/3 4, Phase 2 97, Phase 1/2 19, Phase 1 30) 2003: 372 trials (Observational 48, Not applicable 42, Phase 4 26, Phase 3 63, Phase 2/3 9, Phase 2 134, Phase 1/2 16, Phase 1 34) 2004: 505 trials (Observational 62, Not applicable 72, Phase 4 39, Phase 3 91, Phase 2/3 6, Phase 2 159, Phase 1/2 26, Phase 1 50) 2005: 642 trials (Observational 103, Not applicable 85, Phase 4 46, Phase 3 90, Phase 2/3 13, Phase 2 195, Phase 1/2 37, Phase 1 73) 2006: 749 trials (Other 2, Observational 133, Not applicable 102, Phase 4 52, Phase 3 106, Phase 2/3 14, Phase 2 220, Phase 1/2 39, Phase 1 81) 2007: 833 trials (Observational 146, Not applicable 128, Phase 4 57, Phase 3 94, Phase 2/3 9, Phase 2 249, Phase 1/2 54, Phase 1 96) 2008: 924 trials (Observational 182, Not applicable 142, Phase 4 65, Phase 3 115, Phase 2/3 16, Phase 2 242, Phase 1/2 45, Phase 1 117) 2009: 937 trials (Other 1, Observational 186, Not applicable 161, Phase 4 71, Phase 3 107, Phase 2/3 16, Phase 2 233, Phase 1/2 55, Phase 1 107) 2010: 958 trials (Other 1, Observational 202, Not applicable 193, Phase 4 67, Phase 3 92, Phase 2/3 16, Phase 2 219, Phase 1/2 56, Phase 1 112) 2011: 977 trials (Other 1, Observational 204, Not applicable 194, Phase 4 55, Phase 3 109, Phase 2/3 18, Phase 2 227, Phase 1/2 33, Phase 1 136) 2012: 988 trials (Observational 208, Not applicable 235, Phase 4 38, Phase 3 117, Phase 2/3 20, Phase 2 199, Phase 1/2 49, Phase 1 122) 2013: 1,076 trials (Observational 203, Not applicable 257, Phase 4 49, Phase 3 126, Phase 2/3 10, Phase 2 240, Phase 1/2 41, Phase 1 150) 2014: 1,158 trials (Other 1, Observational 231, Not applicable 293, Phase 4 50, Phase 3 125, Phase 2/3 16, Phase 2 228, Phase 1/2 62, Phase 1 152) 2015: 1,359 trials (Observational 269, Not applicable 378, Phase 4 58, Phase 3 143, Phase 2/3 11, Phase 2 261, Phase 1/2 75, Phase 1 164) 2016: 1,389 trials (Observational 250, Not applicable 419, Phase 4 75, Phase 3 110, Phase 2/3 7, Phase 2 263, Phase 1/2 75, Phase 1 190) 2017: 1,395 trials (Other 1, Observational 265, Not applicable 440, Phase 4 49, Phase 3 118, Phase 2/3 19, Phase 2 261, Phase 1/2 78, Phase 1 164) 2018: 1,479 trials (Observational 306, Not applicable 440, Phase 4 72, Phase 3 145, Phase 2/3 27, Phase 2 228, Phase 1/2 75, Phase 1 186) 2019: 1,610 trials (Observational 376, Not applicable 489, Phase 4 60, Phase 3 116, Phase 2/3 10, Phase 2 284, Phase 1/2 84, Phase 1 191) 2020: 1,526 trials (Observational 347, Not applicable 459, Phase 4 63, Phase 3 100, Phase 2/3 17, Phase 2 269, Phase 1/2 78, Phase 1 193) 2021: 1,821 trials (Observational 450, Not applicable 582, Phase 4 69, Phase 3 132, Phase 2/3 16, Phase 2 304, Phase 1/2 79, Phase 1 189) 2022: 1,904 trials (Observational 443, Not applicable 628, Phase 4 85, Phase 3 146, Phase 2/3 24, Phase 2 271, Phase 1/2 84, Phase 1 223) 2023: 1,849 trials (Observational 435, Not applicable 640, Phase 4 75, Phase 3 143, Phase 2/3 26, Phase 2 264, Phase 1/2 93, Phase 1 173) 2024: 1,879 trials (Observational 413, Not applicable 696, Phase 4 56, Phase 3 140, Phase 2/3 21, Phase 2 263, Phase 1/2 85, Phase 1 205) 2025: 1,951 trials (Observational 447, Not applicable 651, Phase 4 76, Phase 3 164, Phase 2/3 17, Phase 2 299, Phase 1/2 85, Phase 1 212)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1,728
2025 1,951
2024 1,879
2023 1,849
2022 1,904
2021 1,821
2020 1,526
2019 1,610
2018 1,479
2017 1,395

Forecast of the full-year count, planned starts included, not rows of this table: about 2,200 trials starting in 2026 and about 2,000 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 3,153 trials still running at the 2026-10-09 snapshot; registered median of 24 months across 19,345 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Skin Diseases trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 3,680
Phase 1/2 1,607
Phase 2 6,287
Phase 2/3 398
Phase 3 3,136
Phase 4 1,496
Not applicable 8,497
Observational 6,471
Expanded access 81
Unknown 2

How many Skin Diseases trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1,420
Recruiting 3,829
Enrolling by invitation 208
Active, not recruiting 1,709
Available 29

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Skin Diseases trials? (7)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 519
Novartis Pharmaceuticals 421
Pfizer 365
Hoffmann-La Roche 243
AstraZeneca 217

Which drugs are being tested for Skin Diseases? (9)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Cytoxan 673
(nab)-paclitaxel 583
TRASTUZUMAB 547
PEMBROLIZUMAB 473
"Capecitabine" 344

Interventions as named in the registry (6)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Docetetaxel 391
or carboplatin 315
Letrozol (Femara, Novartis) 301
Doxorubicine 284
Tamoxifen Pill 242

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Skin Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 4,089 914
Febrile neutropenia 3,769 485
Pyrexia 3,336 597
Neutropenia 3,298 369
Vomiting 3,005 781

Which publications cover Skin Diseases? (778)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (45)

MeSH descendants one level down with at least one trial, most trials first.

+35 more sub-conditions

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages