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Condition (MeSH)

Skin Diseases, Papulosquamous

ClinicalTrials.gov lists 2,208 trials for Skin Diseases, Papulosquamous or a narrower condition beneath it. Novartis Pharmaceuticals has the most among industry and government lead sponsors, with 71.

MeSH D017444 Skin and Connective Tissue Diseases C17
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Phase 1 Phase 1 220 Phase 1/2 Phase 1/2 34 Phase 2 Phase 2 371 Phase 2/3 Phase 2/3 21 Phase 3 Phase 3 348 Phase 4 Phase 4 250 Not applicable Not applicable 352 Observational Observational 611 Phase 1 Phase 1 220 Phase 1/2 Phase 1/2 34 Phase 2 Phase 2 371 Phase 2/3 Phase 2/3 21 Phase 3 Phase 3 348 Phase 4 Phase 4 250 Not applicable Not applicable 352 Observational Observational 611

Trials per phase (log scale)

1 more section with rows

11 of the 2,208 trials are tagged with Skin Diseases, Papulosquamous itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Skin Diseases, Papulosquamous trials start? (34)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 152

1991: 1 trials (Observational 1) 1993: 1 trials (Observational 1) 1995: 3 trials (Observational 2, Phase 2 1) 1996: 1 trials (Observational 1) 1997: 3 trials (Not applicable 1, Phase 1/2 2) 1998: 1 trials (Not applicable 1) 1999: 1 trials (Phase 2 1) 2000: 9 trials (Observational 1, Not applicable 2, Phase 3 1, Phase 2 2, Phase 1/2 3) 2001: 6 trials (Observational 1, Phase 4 1, Phase 3 1, Phase 2 3) 2002: 13 trials (Observational 6, Phase 4 1, Phase 3 3, Phase 2 1, Phase 1 2) 2003: 24 trials (Observational 3, Phase 4 2, Phase 3 7, Phase 2 12) 2004: 32 trials (Observational 8, Not applicable 3, Phase 4 7, Phase 3 8, Phase 2 6) 2005: 46 trials (Observational 8, Not applicable 3, Phase 4 5, Phase 3 9, Phase 2/3 1, Phase 2 17, Phase 1/2 1, Phase 1 2) 2006: 49 trials (Observational 12, Not applicable 1, Phase 4 8, Phase 3 9, Phase 2/3 1, Phase 2 16, Phase 1 2) 2007: 63 trials (Observational 12, Not applicable 7, Phase 4 9, Phase 3 7, Phase 2/3 1, Phase 2 18, Phase 1/2 4, Phase 1 5) 2008: 62 trials (Observational 15, Not applicable 5, Phase 4 11, Phase 3 10, Phase 2/3 1, Phase 2 14, Phase 1/2 1, Phase 1 5) 2009: 54 trials (Observational 12, Not applicable 3, Phase 4 10, Phase 3 5, Phase 2 16, Phase 1/2 3, Phase 1 5) 2010: 87 trials (Observational 19, Not applicable 11, Phase 4 15, Phase 3 18, Phase 2 19, Phase 1 5) 2011: 68 trials (Observational 17, Not applicable 7, Phase 4 4, Phase 3 15, Phase 2/3 2, Phase 2 13, Phase 1/2 1, Phase 1 9) 2012: 65 trials (Observational 14, Not applicable 7, Phase 4 5, Phase 3 21, Phase 2 9, Phase 1/2 2, Phase 1 7) 2013: 92 trials (Observational 21, Not applicable 12, Phase 4 6, Phase 3 25, Phase 2 16, Phase 1 12) 2014: 87 trials (Observational 13, Not applicable 18, Phase 4 7, Phase 3 21, Phase 2 16, Phase 1/2 1, Phase 1 11) 2015: 97 trials (Observational 34, Not applicable 11, Phase 4 4, Phase 3 20, Phase 2/3 1, Phase 2 16, Phase 1/2 3, Phase 1 8) 2016: 104 trials (Observational 18, Not applicable 15, Phase 4 13, Phase 3 18, Phase 2 23, Phase 1 17) 2017: 107 trials (Observational 29, Not applicable 20, Phase 4 12, Phase 3 16, Phase 2/3 2, Phase 2 14, Phase 1/2 4, Phase 1 10) 2018: 116 trials (Observational 22, Not applicable 17, Phase 4 16, Phase 3 20, Phase 2/3 2, Phase 2 17, Phase 1 22) 2019: 152 trials (Observational 42, Not applicable 22, Phase 4 17, Phase 3 25, Phase 2/3 1, Phase 2 23, Phase 1/2 2, Phase 1 20) 2020: 112 trials (Observational 45, Not applicable 21, Phase 4 17, Phase 3 6, Phase 2/3 1, Phase 2 15, Phase 1 7) 2021: 138 trials (Observational 57, Not applicable 19, Phase 4 16, Phase 3 17, Phase 2 14, Phase 1/2 2, Phase 1 13) 2022: 122 trials (Observational 39, Not applicable 26, Phase 4 16, Phase 3 8, Phase 2/3 1, Phase 2 15, Phase 1 17) 2023: 129 trials (Observational 52, Not applicable 30, Phase 4 13, Phase 3 12, Phase 2/3 1, Phase 2 14, Phase 1/2 2, Phase 1 5) 2024: 106 trials (Observational 32, Not applicable 27, Phase 4 5, Phase 3 17, Phase 2/3 2, Phase 2 9, Phase 1/2 2, Phase 1 12) 2025: 123 trials (Observational 40, Not applicable 33, Phase 4 7, Phase 3 14, Phase 2/3 3, Phase 2 11, Phase 1 15)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 118
2025 123
2024 106
2023 129
2022 122
2021 138
2020 112
2019 152
2018 116
2017 107

Forecast of the full-year count, planned starts included, not rows of this table: about 130 trials starting in 2026 and about 120 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 33 months from start to primary completion across 152 trials still running at the 2026-10-09 snapshot; registered median of 17 months across 1,512 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Skin Diseases, Papulosquamous trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 220
Phase 1/2 34
Phase 2 371
Phase 2/3 21
Phase 3 348
Phase 4 250
Not applicable 352
Observational 611
Expanded access 1

How many Skin Diseases, Papulosquamous trials are recruiting? (10)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 86
Recruiting 212
Enrolling by invitation 15
Active, not recruiting 72
Available 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Skin Diseases, Papulosquamous trials? (13)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Novartis Pharmaceuticals 71
AbbVie 64
Amgen 62
Pfizer 53
Bristol-Myers Squibb 39

Which drugs are being tested for Skin Diseases, Papulosquamous? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
INFLIXIMAB 34
(CP-6890,550) Tofacitinib 26

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Secukinmab 90
Adalimumab-US 80
1=Etanercept 77
HD- Methotrexate (MTX) 60
Apremilast IR 59

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Skin Diseases, Papulosquamous trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Invasive cancer of any type 1,617 1
Major cardiovascular event 805 1
Gastrointestinal bleeding 744 1
Myocardial infarction 530 71
Prostate cancer (in men) 411 1

Which publications cover Skin Diseases, Papulosquamous? (1)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
What's new in objective assessment and treatment of facial hyperpigmentation? Dermatologic clinics 2014 No

Sub-conditions in MeSH (5)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages