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Condition (MeSH)

Sexually Transmitted Diseases

ClinicalTrials.gov lists 7,865 trials for Sexually Transmitted Diseases or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 1,084.

MeSH D012749 Infections C01 C12 C23
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Phase 1 Phase 1 1,139 Phase 1/2 Phase 1/2 226 Phase 2 Phase 2 974 Phase 2/3 Phase 2/3 95 Phase 3 Phase 3 795 Phase 4 Phase 4 654 Not applicable Not applicable 2,423 Observational Observational 1,544 Phase 1 Phase 1 1,139 Phase 1/2 Phase 1/2 226 Phase 2 Phase 2 974 Phase 2/3 Phase 2/3 95 Phase 3 Phase 3 795 Phase 4 Phase 4 654 Not applicable Not applicable 2,423 Observational Observational 1,544

Trials per phase (log scale)

1 more section with rows

519 of the 7,865 trials are tagged with Sexually Transmitted Diseases itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Sexually Transmitted Diseases trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 23 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access)

Top of scale: 364

1990: 5 trials (Observational 1, Phase 3 2, Phase 2 2) 1991: 2 trials (Phase 3 1, Phase 2 1) 1992: 8 trials (Observational 5, Not applicable 1, Phase 3 2) 1993: 4 trials (Observational 1, Phase 3 1, Phase 2 2) 1994: 16 trials (Observational 7, Not applicable 3, Phase 4 2, Phase 2/3 1, Phase 1 3) 1995: 15 trials (Observational 4, Not applicable 2, Phase 3 1, Phase 2/3 1, Phase 2 4, Phase 1 3) 1996: 18 trials (Observational 7, Phase 4 1, Phase 3 3, Phase 2/3 1, Phase 2 4, Phase 1 2) 1997: 33 trials (Observational 11, Not applicable 3, Phase 3 7, Phase 2 3, Phase 1/2 3, Phase 1 6) 1998: 28 trials (Observational 10, Not applicable 3, Phase 4 2, Phase 3 3, Phase 2 5, Phase 1 5) 1999: 79 trials (Observational 14, Not applicable 10, Phase 4 7, Phase 3 14, Phase 2/3 1, Phase 2 20, Phase 1 13) 2000: 73 trials (Other 1, Observational 19, Not applicable 6, Phase 4 5, Phase 3 18, Phase 2 14, Phase 1/2 2, Phase 1 8) 2001: 95 trials (Other 1, Observational 20, Not applicable 14, Phase 4 6, Phase 3 23, Phase 2/3 4, Phase 2 19, Phase 1/2 5, Phase 1 3) 2002: 132 trials (Other 1, Observational 30, Not applicable 24, Phase 4 14, Phase 3 25, Phase 2/3 4, Phase 2 24, Phase 1/2 3, Phase 1 7) 2003: 175 trials (Other 1, Observational 31, Not applicable 32, Phase 4 23, Phase 3 29, Phase 2/3 3, Phase 2 32, Phase 1/2 7, Phase 1 17) 2004: 220 trials (Other 2, Observational 39, Not applicable 29, Phase 4 33, Phase 3 42, Phase 2/3 6, Phase 2 39, Phase 1/2 7, Phase 1 23) 2005: 267 trials (Observational 54, Not applicable 36, Phase 4 47, Phase 3 36, Phase 2/3 4, Phase 2 50, Phase 1/2 11, Phase 1 29) 2006: 267 trials (Observational 44, Not applicable 42, Phase 4 39, Phase 3 35, Phase 2/3 6, Phase 2 46, Phase 1/2 15, Phase 1 40) 2007: 293 trials (Observational 60, Not applicable 47, Phase 4 33, Phase 3 52, Phase 2/3 8, Phase 2 40, Phase 1/2 12, Phase 1 41) 2008: 299 trials (Observational 69, Not applicable 56, Phase 4 53, Phase 3 33, Phase 2/3 5, Phase 2 37, Phase 1/2 9, Phase 1 37) 2009: 364 trials (Observational 86, Not applicable 63, Phase 4 47, Phase 3 41, Phase 2/3 6, Phase 2 59, Phase 1/2 11, Phase 1 51) 2010: 280 trials (Observational 72, Not applicable 49, Phase 4 35, Phase 3 31, Phase 2/3 2, Phase 2 32, Phase 1/2 14, Phase 1 45) 2011: 251 trials (Observational 55, Not applicable 60, Phase 4 25, Phase 3 40, Phase 2/3 4, Phase 2 16, Phase 1/2 8, Phase 1 43) 2012: 208 trials (Other 1, Observational 54, Not applicable 67, Phase 4 11, Phase 3 23, Phase 2/3 4, Phase 2 21, Phase 1/2 5, Phase 1 22) 2013: 196 trials (Observational 41, Not applicable 75, Phase 4 12, Phase 3 15, Phase 2/3 4, Phase 2 15, Phase 1/2 8, Phase 1 26) 2014: 195 trials (Observational 35, Not applicable 54, Phase 4 14, Phase 3 18, Phase 2/3 3, Phase 2 23, Phase 1/2 11, Phase 1 37) 2015: 245 trials (Observational 44, Not applicable 91, Phase 4 18, Phase 3 15, Phase 2/3 1, Phase 2 27, Phase 1/2 5, Phase 1 44) 2016: 223 trials (Observational 37, Not applicable 85, Phase 4 16, Phase 3 17, Phase 2/3 7, Phase 2 18, Phase 1/2 7, Phase 1 36) 2017: 293 trials (Observational 59, Not applicable 136, Phase 4 18, Phase 3 14, Phase 2/3 1, Phase 2 18, Phase 1/2 8, Phase 1 39) 2018: 268 trials (Observational 59, Not applicable 112, Phase 4 24, Phase 3 12, Phase 2/3 3, Phase 2 16, Phase 1/2 10, Phase 1 32) 2019: 317 trials (Observational 72, Not applicable 139, Phase 4 18, Phase 3 16, Phase 2/3 2, Phase 2 23, Phase 1/2 9, Phase 1 38) 2020: 261 trials (Observational 61, Not applicable 101, Phase 4 28, Phase 3 21, Phase 2/3 2, Phase 2 19, Phase 1/2 5, Phase 1 24) 2021: 305 trials (Observational 74, Not applicable 127, Phase 4 31, Phase 3 18, Phase 2/3 2, Phase 2 24, Phase 1/2 4, Phase 1 25) 2022: 294 trials (Observational 72, Not applicable 136, Phase 4 19, Phase 3 13, Phase 2/3 3, Phase 2 17, Phase 1/2 6, Phase 1 28) 2023: 300 trials (Observational 70, Not applicable 147, Phase 4 22, Phase 3 15, Phase 2/3 2, Phase 2 19, Phase 1/2 6, Phase 1 19) 2024: 248 trials (Observational 54, Not applicable 127, Phase 4 10, Phase 3 11, Phase 2/3 2, Phase 2 15, Phase 1/2 8, Phase 1 21) 2025: 206 trials (Observational 50, Not applicable 98, Phase 4 14, Phase 3 9, Phase 2/3 2, Phase 2 13, Phase 1/2 5, Phase 1 15)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 205
2025 206
2024 248
2023 300
2022 294
2021 305
2020 261
2019 317
2018 268
2017 293

Forecast of the full-year count, planned starts included, not rows of this table: about 220 trials starting in 2026 and about 220 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 410 trials still running at the 2026-10-09 snapshot; registered median of 25 months across 4,742 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Sexually Transmitted Diseases trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1,139
Phase 1/2 226
Phase 2 974
Phase 2/3 95
Phase 3 795
Phase 4 654
Not applicable 2,423
Observational 1,544
Expanded access 15

How many Sexually Transmitted Diseases trials are recruiting? (12)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 184
Recruiting 403
Enrolling by invitation 37
Active, not recruiting 216
Available 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Sexually Transmitted Diseases trials? (10)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Institute of Allergy and Infectious Diseases (NIAID) 1,084
ViiV Healthcare 248
Merck Sharp & Dohme LLC 140
GlaxoSmithKline 134
National Cancer Institute (NCI) 92

Which drugs are being tested for Sexually Transmitted Diseases? (7)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Zidovudine 277
LAMIVUDINE 179
Efavirenz 144
Raltegravir 107
Nelfinavir 84

Interventions as named in the registry (8)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Ritonavir (RTV) low 164
didanosine, ddI (drug) 120
Stavudine 113
Nevirapine IR 109
Dolutegravir Pill 95

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Sexually Transmitted Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 1,394 230
Any Event in SOC 823 16
Gastroenteritis 792 152
Road traffic accident 743 51
Appendicitis 723 153

Which publications cover Sexually Transmitted Diseases? (730)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages