Condition (MeSH)
Stomatitis, Aphthous
ClinicalTrials.gov lists 60 trials for Stomatitis, Aphthous or a narrower condition beneath it.
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Trials per phase
60 of the 60 trials are tagged with Stomatitis, Aphthous itself; the rest are tagged with a narrower condition beneath it.
When did Stomatitis, Aphthous trials start? (22)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 5 |
| 2025 | 5 |
| 2024 | 6 |
| 2023 | 6 |
| 2022 | 2 |
| 2021 | 3 |
| 2020 | 1 |
| 2019 | 2 |
| 2018 | 7 |
| 2017 | 1 |
Showing 10 of 22 earlier years.
No forecast is made for this condition: it averages 4.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Stomatitis, Aphthous trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 4 |
| Phase 1/2 | 2 |
| Phase 2 | 15 |
| Phase 3 | 3 |
| Phase 4 | 4 |
| Not applicable | 26 |
| Observational | 6 |
How many Stomatitis, Aphthous trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 5 |
| Recruiting | 5 |
| Completed | 35 |
| Suspended | 1 |
| Terminated | 1 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Stomatitis, Aphthous trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| EMS | 2 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 2 |
| National Institute of Dental and Craniofacial Research (NIDCR) | 2 |
| Devintec Sagl | 1 |
| Faculty of Dental Medicine for Girls | 1 |
Which drugs are being tested for Stomatitis, Aphthous? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| THALIDOMIDE | 3 |
Interventions as named in the registry (14)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Low Level Laser Therapy | 1 |
| Anakinra alone (stages 2b/3) | 1 |
| fatty acids, omega-3 | 1 |
| Oromucoadhesive film | 1 |
| GV-328 | 1 |
Showing 5 of 14 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Stomatitis, Aphthous trials report? (4)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Chest wall pain | 1 | 1 |
| Presyncope | 1 | 1 |
| Pulmonary hypertension | 1 | 1 |
| Thromboembolic event | 1 | 1 |
Which publications cover Stomatitis, Aphthous? (79)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Systemic and local effect of oxidative stress on recurrent aphthous stomatitis: systematic review. | Journal of molecular medicine (Berlin, Germany) | 2024 | Yes |
| Efficacy of curcumin for recurrent aphthous stomatitis: a systematic review. | The Journal of dermatological treatment | 2022 | Yes |
| Evaluation of diode laser versus topical corticosteroid in management of Behcet's disease-associated oral ulcers: a randomized clinical trial. | Clinical oral investigations | 2022 | Yes |
| IL-10 and TGF-β1 gene polymorphisms in Greek patients with recurrent aphthous stomatitis. | Medicina oral, patologia oral y cirugia bucal | 2022 | Yes |
| Topical NAVS naphthalan for the treatment of oral lichen planus and recurrent aphthous stomatitis: A double blind, randomized, parallel group study. | PloS one | 2021 | Yes |
Showing 5 of 79 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.