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Condition (MeSH)

Tinnitus

ClinicalTrials.gov lists 424 trials for Tinnitus or a narrower condition beneath it. VA Office of Research and Development has the most among industry and government lead sponsors, with 8.

MeSH D014012 Otorhinolaryngologic Diseases C09 C10 C23
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Phase 1 Phase 1 17 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 39 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 18 Phase 4 Phase 4 17 Not applicable Not applicable 264 Observational Observational 56 Phase 1 Phase 1 17 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 39 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 18 Phase 4 Phase 4 17 Not applicable Not applicable 264 Observational Observational 56

Trials per phase (log scale)

424 of the 424 trials are tagged with Tinnitus itself; the rest are tagged with a narrower condition beneath it.

Get the Tinnitus report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Tinnitus trials start? (26)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 4 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 32

1999: 2 trials (Observational 1, Phase 2 1) 2000: 1 trials (Phase 4 1) 2003: 1 trials (Phase 2 1) 2004: 3 trials (Not applicable 1, Phase 2/3 1, Phase 2 1) 2005: 3 trials (Phase 2 2, Phase 1 1) 2006: 6 trials (Not applicable 3, Phase 2 2, Phase 1 1) 2007: 6 trials (Observational 1, Not applicable 2, Phase 4 1, Phase 2/3 1, Phase 2 1) 2008: 16 trials (Not applicable 8, Phase 4 1, Phase 3 2, Phase 2 4, Phase 1 1) 2009: 14 trials (Observational 3, Not applicable 4, Phase 4 1, Phase 3 2, Phase 2 2, Phase 1/2 1, Phase 1 1) 2010: 15 trials (Observational 3, Not applicable 9, Phase 2/3 1, Phase 1 2) 2011: 18 trials (Observational 4, Not applicable 4, Phase 4 1, Phase 3 4, Phase 2 3, Phase 1/2 2) 2012: 18 trials (Observational 2, Not applicable 11, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 2) 2013: 12 trials (Not applicable 9, Phase 2 2, Phase 1 1) 2014: 24 trials (Observational 2, Not applicable 10, Phase 4 2, Phase 3 4, Phase 2 4, Phase 1 2) 2015: 11 trials (Observational 1, Not applicable 8, Phase 1/2 1, Phase 1 1) 2016: 18 trials (Observational 4, Not applicable 12, Phase 4 2) 2017: 20 trials (Observational 1, Not applicable 16, Phase 2 3) 2018: 27 trials (Observational 4, Not applicable 21, Phase 1 2) 2019: 22 trials (Observational 5, Not applicable 13, Phase 4 1, Phase 2 2, Phase 1/2 1) 2020: 13 trials (Observational 3, Not applicable 9, Phase 3 1) 2021: 25 trials (Observational 2, Not applicable 18, Phase 4 3, Phase 2 1, Phase 1 1) 2022: 32 trials (Observational 6, Not applicable 23, Phase 3 1, Phase 2 2) 2023: 25 trials (Observational 6, Not applicable 13, Phase 3 1, Phase 2 2, Phase 1 3) 2024: 27 trials (Observational 4, Not applicable 20, Phase 3 1, Phase 2/3 1, Phase 1/2 1) 2025: 29 trials (Observational 1, Not applicable 26, Phase 4 1, Phase 3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 31
2025 29
2024 27
2023 25
2022 32
2021 25
2020 13
2019 22
2018 27
2017 20

Forecast of the full-year count, planned starts included, not rows of this table: about 39 trials starting in 2026 and about 34 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 28 months from start to primary completion across 34 trials still running at the 2026-10-09 snapshot; registered median of 17 months across 258 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Tinnitus trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 17
Phase 1/2 8
Phase 2 39
Phase 2/3 5
Phase 3 18
Phase 4 17
Not applicable 264
Observational 56

How many Tinnitus trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 29
Recruiting 40
Enrolling by invitation 7
Active, not recruiting 6
Completed 240

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Tinnitus trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
VA Office of Research and Development 8
Sound Pharmaceuticals, Incorporated 6
US Department of Veterans Affairs 6
Merz Pharmaceuticals GmbH 5

Which drugs are being tested for Tinnitus? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Esketamine 5
Neramexane 5
Ebselen 4
OTO-313 3

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Acupuncture 6
Ginkgo biloba pills 4
Dexamethasone/Dexamethasone acetate 3
Transcranial Magnetic Stimulation 3
Gabapentin 6% 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Tinnitus trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Infective pulmonary exacerbation of cystic fibrosis 3 1
Cancer 2 1
Deep vein thrombosis 2 2
Diverticulitis 2 2
Hoarseness 2 1

Which publications cover Tinnitus? (508)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages