Condition (MeSH)
Urethral Obstruction
ClinicalTrials.gov lists 115 trials for Urethral Obstruction or a narrower condition beneath it. Urotronic Inc. has the most among industry and government lead sponsors, with 5.
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Trials per phase (log scale)
4 of the 115 trials are tagged with Urethral Obstruction itself; the rest are tagged with a narrower condition beneath it.
When did Urethral Obstruction trials start? (25)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 12
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 16 |
| 2025 | 6 |
| 2024 | 8 |
| 2023 | 6 |
| 2022 | 12 |
| 2021 | 2 |
| 2020 | 10 |
| 2019 | 4 |
| 2018 | 7 |
| 2017 | 5 |
Showing 10 of 25 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 19 trials starting in 2026 and about 12 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Urethral Obstruction trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 8 |
| Phase 1/2 | 2 |
| Phase 2 | 7 |
| Phase 2/3 | 2 |
| Phase 3 | 7 |
| Phase 4 | 10 |
| Not applicable | 54 |
| Observational | 25 |
How many Urethral Obstruction trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 11 |
| Recruiting | 14 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 8 |
| Completed | 46 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Urethral Obstruction trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Urotronic Inc. | 5 |
| Astellas Pharma Inc | 2 |
| Nymox Corporation | 2 |
Which drugs are being tested for Urethral Obstruction? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| NX-1207 | 2 |
| Tamsulosin | 2 |
| +/- Bupivacaine HCl | 2 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Mitomycin C 0.02% | 2 |
| Solifenacin PO | 2 |
| Gabapentin 6% | 2 |
| Autologous Engineered Urethral Construct | 1 |
| Basic buccal procedure + Buccal block | 1 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Urethral Obstruction trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Urinary Tract Infection | 3 | 2 |
| Abdominal Pain | 2 | 2 |
| COVID-19 | 2 | 1 |
| Urinary Retention | 2 | 1 |
| Accidental overdose | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Urethral Obstruction? (36)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Ejaculatory function following transperineal laser ablation vs TURP for benign prostatic obstruction: a randomized trial. | BJU international | 2023 | Yes |
| Holmium Laser Xpeeda Vaporization <i>vs</i> GreenLight XPS Vaporization of the Prostate for Benign Prostatic Obstruction: 1-Year Results from a Randomized Controlled Clinical Study. | Journal of endourology | 2023 | Yes |
| Definition, diagnosis and management of fetal lower urinary tract obstruction: consensus of the ERKNet CAKUT-Obstructive Uropathy Work Group. | Nature reviews. Urology | 2022 | Yes |
| Longitudinal kidney injury biomarker trajectories in children with obstructive uropathy. | Pediatric nephrology (Berlin, Germany) | 2020 | Yes |
| Minimally invasive prostatic urethral lift (PUL) efficacious in TURP candidates: a multicenter German evaluation after 2 years. | World journal of urology | 2019 | Yes |
Showing 5 of 36 publications.
Sub-conditions in MeSH (2)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.