Condition (MeSH)
Urethral Stricture
ClinicalTrials.gov lists 66 trials for Urethral Stricture or a narrower condition beneath it. Urotronic Inc. has the most among industry and government lead sponsors, with 5.
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Trials per phase (log scale)
66 of the 66 trials are tagged with Urethral Stricture itself; the rest are tagged with a narrower condition beneath it.
When did Urethral Stricture trials start? (16)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 11
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 10 |
| 2025 | 3 |
| 2024 | 5 |
| 2023 | 4 |
| 2022 | 11 |
| 2021 | 1 |
| 2020 | 8 |
| 2019 | 4 |
| 2018 | 2 |
| 2017 | 4 |
Showing 10 of 16 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 12 trials starting in 2026 and about 7 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Urethral Stricture trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 4 |
| Phase 1/2 | 1 |
| Phase 2 | 5 |
| Phase 2/3 | 2 |
| Phase 3 | 5 |
| Phase 4 | 5 |
| Not applicable | 35 |
| Observational | 9 |
How many Urethral Stricture trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 7 |
| Recruiting | 9 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 6 |
| Completed | 24 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Urethral Stricture trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Urotronic Inc. | 5 |
| Hannes Kortekangas | 1 |
Which drugs are being tested for Urethral Stricture? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| +/- Bupivacaine HCl | 2 |
Interventions as named in the registry (14)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Mitomycin C 0.02% | 2 |
| Autologous Engineered Urethral Construct | 1 |
| Basic buccal procedure + Buccal block | 1 |
| DVIU treated with liquid buccal mucosal graft | 1 |
| [PRP] platelet rich plasma | 1 |
Showing 5 of 14 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Urethral Stricture trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Urinary Tract Infection | 3 | 2 |
| Abdominal Pain | 2 | 2 |
| COVID-19 | 2 | 1 |
| Urinary Retention | 2 | 1 |
| Anesthetic Complication - Pulmonary | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Urethral Stricture? (86)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Treatment of bulbar urethral strictures with Optilume drug-coated balloons in a previously untreated population (FIRST-CARE): protocol for a single-blind multicentre randomised controlled trial. | BMJ open | 2026 | Yes |
| Long-Term Outcomes of Recurrent Bulbar Urethral Stricture Treatment With the Optilume Drug-Coated Balloon: Five-Year Results From the ROBUST I Study. | The Journal of urology | 2025 | Yes |
| Determining the outcomes of urethral construction in phalloplasty. | BJU international | 2023 | Yes |
| Urethrocystography: a guide for urological surgery? | Diagnostic and interventional radiology (Ankara, Turkey) | 2023 | Yes |
| One-Year Results for the ROBUST III Randomized Controlled Trial Evaluating the Optilume<sup>®</sup> Drug-Coated Balloon for Anterior Urethral Strictures. | The Journal of urology | 2022 | Yes |
Showing 5 of 86 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.