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Condition (MeSH)

Velopharyngeal Insufficiency

ClinicalTrials.gov lists 20 trials for Velopharyngeal Insufficiency or a narrower condition beneath it.

MeSH D014681 Stomatognathic Diseases C07 C09 C16 Listed by Orphanet as a rare disease
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Not applicable Not applicable 13 Observational Observational 7 Not applicable Not applicable 13 Observational Observational 7

Trials per phase

20 of the 20 trials are tagged with Velopharyngeal Insufficiency itself; the rest are tagged with a narrower condition beneath it.

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When did Velopharyngeal Insufficiency trials start? (11)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Not applicable
  • Observational

Top of scale: 3

2005: 1 trials (Observational 1) 2016: 2 trials (Not applicable 2) 2017: 2 trials (Observational 1, Not applicable 1) 2018: 3 trials (Observational 1, Not applicable 2) 2019: 1 trials (Not applicable 1) 2020: 1 trials (Not applicable 1) 2022: 2 trials (Observational 1, Not applicable 1) 2023: 1 trials (Not applicable 1) 2024: 1 trials (Not applicable 1) 2025: 1 trials (Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 5
2025 1
2024 1
2023 1
2022 2
2020 1
2019 1
2018 3
2017 2
2016 2

No forecast is made for this condition: it averages 1.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Velopharyngeal Insufficiency trials in? (2)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Not applicable 13
Observational 7

How many Velopharyngeal Insufficiency trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 4
Completed 4
Terminated 3
Unknown status 6

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which publications cover Velopharyngeal Insufficiency? (38)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Normative data on nasalance scores for French speaking children. Journal of stomatology, oral and maxillofacial surgery 2025 Yes
MRI assessment of velopharyngeal dysfunction: A comprehensive primer for radiologists. Pediatric radiology 2025 Yes
Velopharyngeal Function Post Head and Neck Cancer: A Review. Ear, nose, & throat journal 2024 Yes
Establishing a Clinical Protocol for Velopharyngeal MRI and Interpreting Imaging Findings. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2024 Yes
How differences in anatomy and physiology and other aetiology affect the way we label and describe speech in individuals with cleft lip and palate. International journal of language & communication disorders 2024 Yes

Prevalence (2)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Congenital velopharyngeal incompetence Point prevalence <1 / 1 000 000 Worldwide Not stated Unspecified
Congenital velopharyngeal incompetence Cases families Worldwide Not stated Unspecified

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, drugs tested, serious adverse events in this condition's trials, rare-disease identity, and sub-conditions in mesh.

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