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Condition (MeSH)

Werner Syndrome

ClinicalTrials.gov lists 4 trials for Werner Syndrome or a narrower condition beneath it. PRG Science & Technology Co., Ltd. has the most among industry and government lead sponsors, with 2.

MeSH D014898 Congenital / Hereditary / Neonatal C16 C18 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Not applicable Not applicable 1 Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Not applicable Not applicable 1

Trials per phase

4 of the 4 trials are tagged with Werner Syndrome itself; the rest are tagged with a narrower condition beneath it.

Get the Werner Syndrome report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Werner Syndrome trials start? (4)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Not applicable

Top of scale: 1

1992: 1 trials (Not applicable 1) 2020: 1 trials (Phase 1 1) 2025: 1 trials (Phase 1/2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 1
2020 1
1992 1

No forecast is made for this condition: it averages 0.2 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Werner Syndrome trials in? (4)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 1/2 1
Phase 2 1
Not applicable 1

How many Werner Syndrome trials are recruiting? (2)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 2
Completed 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Werner Syndrome trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
PRG Science & Technology Co., Ltd. 2
National Center for Research Resources (NCRR) 1
Nimbus Wadjet, Inc. 1

Which publications cover Werner Syndrome? (3)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex. The Journal of biological chemistry 2001 Yes
Clinical features and genetic predisposition to hereditary nonmedullary thyroid cancer. Thyroid : official journal of the American Thyroid Association 2009 No
The premature aging syndromes. Clinics in dermatology 1996 No

Prevalence (12)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Werner syndrome Point prevalence 1-9 / 1 000 000 United States US Exact
Werner syndrome Point prevalence 1-9 / 1 000 000 United States US Unspecified
Werner syndrome Point prevalence 1-9 / 1 000 000 United States US Exact
Werner syndrome Point prevalence 1-9 / 100 000 Japan Not stated Exact
Werner syndrome Point prevalence 1-9 / 1 000 000 Europe Not stated Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Werner syndrome 902 Exact Orphanet Rare Disease Ontology (ORDO)
Werner syndrome 902 Exact Orphadata Science knowledge files, Product 1

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.

Not computed for conditions with fewer than 10 trials: drugs tested.

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