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Condition (MeSH)

Wolff-Parkinson-White Syndrome

ClinicalTrials.gov lists 14 trials for Wolff-Parkinson-White Syndrome or a narrower condition beneath it.

MeSH D014927 Cardiovascular Diseases C14 C16 Listed by Orphanet as a rare disease
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Phase 1/2 Phase 1/2 1 Not applicable Not applicable 5 Observational Observational 8 Phase 1/2 Phase 1/2 1 Not applicable Not applicable 5 Observational Observational 8

Trials per phase

14 of the 14 trials are tagged with Wolff-Parkinson-White Syndrome itself; the rest are tagged with a narrower condition beneath it.

Get the Wolff-Parkinson-White Syndrome report as a PDF

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When did Wolff-Parkinson-White Syndrome trials start? (10)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Not applicable
  • Observational

Top of scale: 2

2005: 1 trials (Not applicable 1) 2009: 1 trials (Not applicable 1) 2016: 1 trials (Observational 1) 2017: 1 trials (Not applicable 1) 2018: 2 trials (Not applicable 2) 2020: 1 trials (Observational 1) 2022: 1 trials (Observational 1) 2023: 2 trials (Observational 2) 2024: 2 trials (Observational 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 2
2024 2
2023 2
2022 1
2020 1
2018 2
2017 1
2016 1
2009 1
2005 1

No forecast is made for this condition: it averages 1.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 14 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Wolff-Parkinson-White Syndrome trials in? (3)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1/2 1
Not applicable 5
Observational 8

How many Wolff-Parkinson-White Syndrome trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 3
Active, not recruiting 1
Completed 4
Terminated 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Wolff-Parkinson-White Syndrome trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Atrium Therapeutics 1
Sykehuset Telemark 1
United States Naval Medical Center, San Diego 1

Interventions as named in the registry (3)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
CRYOTHERAPY 2
ATR 1072 1
Radiofrequency 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Wolff-Parkinson-White Syndrome? (29)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Risk assessment in patients with symptomatic and asymptomatic pre-excitation. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2024 Yes
The Wolff-Parkinson-White pattern in neonates: results from a large population-based cohort study. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2023 Yes
The advantage of the mini-electrode-equipped catheter for the radiofrequency ablation of paroxysmal supraventricular tachycardia. Journal of cardiovascular electrophysiology 2022 Yes
The impact of left ventricular deformation and dyssynchrony on improvement of left ventricular ejection fraction following radiofrequency catheter ablation in Wolff-Parkinson-White syndrome: A comprehensive study by speckle tracking echocardiography. Echocardiography (Mount Kisco, N.Y.) 2017 Yes
Radiofrequency catheter ablation at the non-coronary cusp for the treatment of para-hisian accessory pathways. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2015 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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