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Condition (MeSH)

Arrhythmias, Cardiac

ClinicalTrials.gov lists 5,739 trials for Arrhythmias, Cardiac or a narrower condition beneath it. Abbott Medical Devices has the most among industry and government lead sponsors, with 123.

MeSH D001145 Cardiovascular Diseases C14 C23
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Phase 1 Phase 1 89 Phase 1/2 Phase 1/2 28 Phase 2 Phase 2 192 Phase 2/3 Phase 2/3 34 Phase 3 Phase 3 304 Phase 4 Phase 4 498 Not applicable Not applicable 2,435 Observational Observational 2,155 Phase 1 Phase 1 89 Phase 1/2 Phase 1/2 28 Phase 2 Phase 2 192 Phase 2/3 Phase 2/3 34 Phase 3 Phase 3 304 Phase 4 Phase 4 498 Not applicable Not applicable 2,435 Observational Observational 2,155

Trials per phase (log scale)

2 more sections with rows

1,045 of the 5,739 trials are tagged with Arrhythmias, Cardiac itself; the rest are tagged with a narrower condition beneath it.

Get the Arrhythmias, Cardiac report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Arrhythmias, Cardiac trials start? (36)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 17 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 367

1990: 4 trials (Observational 3, Phase 3 1) 1991: 1 trials (Phase 3 1) 1992: 6 trials (Observational 4, Phase 3 2) 1993: 3 trials (Observational 3) 1995: 5 trials (Observational 2, Not applicable 1, Phase 3 2) 1996: 6 trials (Observational 5, Not applicable 1) 1997: 5 trials (Observational 1, Phase 4 2, Phase 3 1, Phase 1/2 1) 1998: 8 trials (Observational 6, Phase 3 1, Phase 2/3 1) 1999: 12 trials (Observational 3, Not applicable 1, Phase 4 1, Phase 3 3, Phase 2/3 1, Phase 2 3) 2000: 16 trials (Observational 5, Not applicable 3, Phase 4 4, Phase 3 4) 2001: 21 trials (Observational 6, Not applicable 1, Phase 4 4, Phase 3 7, Phase 2 3) 2002: 29 trials (Observational 11, Not applicable 11, Phase 4 4, Phase 3 3) 2003: 57 trials (Observational 15, Not applicable 12, Phase 4 20, Phase 3 6, Phase 2/3 1, Phase 2 3) 2004: 64 trials (Observational 19, Not applicable 12, Phase 4 19, Phase 3 11, Phase 2/3 2, Phase 2 1) 2005: 84 trials (Observational 22, Not applicable 19, Phase 4 12, Phase 3 12, Phase 2/3 2, Phase 2 13, Phase 1/2 1, Phase 1 3) 2006: 93 trials (Observational 26, Not applicable 24, Phase 4 13, Phase 3 15, Phase 2 10, Phase 1 5) 2007: 118 trials (Observational 29, Not applicable 39, Phase 4 22, Phase 3 13, Phase 2 10, Phase 1/2 2, Phase 1 3) 2008: 122 trials (Observational 34, Not applicable 32, Phase 4 25, Phase 3 14, Phase 2/3 3, Phase 2 10, Phase 1 4) 2009: 139 trials (Observational 49, Not applicable 42, Phase 4 20, Phase 3 14, Phase 2/3 1, Phase 2 8, Phase 1/2 1, Phase 1 4) 2010: 149 trials (Observational 52, Not applicable 47, Phase 4 20, Phase 3 16, Phase 2 8, Phase 1/2 2, Phase 1 4) 2011: 175 trials (Observational 71, Not applicable 58, Phase 4 22, Phase 3 6, Phase 2 14, Phase 1/2 2, Phase 1 2) 2012: 220 trials (Observational 66, Not applicable 88, Phase 4 35, Phase 3 17, Phase 2 10, Phase 1 4) 2013: 218 trials (Observational 86, Not applicable 80, Phase 4 18, Phase 3 16, Phase 2/3 1, Phase 2 11, Phase 1 6) 2014: 249 trials (Observational 103, Not applicable 85, Phase 4 22, Phase 3 17, Phase 2 10, Phase 1/2 2, Phase 1 10) 2015: 268 trials (Observational 104, Not applicable 117, Phase 4 25, Phase 3 7, Phase 2/3 1, Phase 2 5, Phase 1/2 3, Phase 1 6) 2016: 280 trials (Observational 119, Not applicable 118, Phase 4 25, Phase 3 7, Phase 2/3 1, Phase 2 6, Phase 1/2 3, Phase 1 1) 2017: 285 trials (Other 1, Observational 126, Not applicable 119, Phase 4 15, Phase 3 10, Phase 2/3 1, Phase 2 7, Phase 1 6) 2018: 332 trials (Other 1, Observational 147, Not applicable 141, Phase 4 24, Phase 3 12, Phase 2/3 2, Phase 2 4, Phase 1/2 1) 2019: 312 trials (Observational 114, Not applicable 150, Phase 4 24, Phase 3 13, Phase 2/3 1, Phase 2 5, Phase 1/2 1, Phase 1 4) 2020: 318 trials (Observational 138, Not applicable 151, Phase 4 15, Phase 3 5, Phase 2/3 2, Phase 2 5, Phase 1 2) 2021: 358 trials (Observational 155, Not applicable 160, Phase 4 19, Phase 3 12, Phase 2/3 1, Phase 2 6, Phase 1/2 2, Phase 1 3) 2022: 355 trials (Observational 144, Not applicable 170, Phase 4 14, Phase 3 14, Phase 2/3 1, Phase 2 4, Phase 1/2 1, Phase 1 7) 2023: 367 trials (Observational 137, Not applicable 186, Phase 4 18, Phase 3 10, Phase 2/3 2, Phase 2 8, Phase 1/2 1, Phase 1 5) 2024: 352 trials (Observational 127, Not applicable 183, Phase 4 15, Phase 3 10, Phase 2/3 4, Phase 2 6, Phase 1/2 2, Phase 1 5) 2025: 340 trials (Observational 103, Not applicable 193, Phase 4 18, Phase 3 5, Phase 2/3 3, Phase 2 13, Phase 1/2 1, Phase 1 4)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 317
2025 340
2024 352
2023 367
2022 355
2021 358
2020 318
2019 312
2018 332
2017 285

Forecast of the full-year count, planned starts included, not rows of this table: about 370 trials starting in 2026 and about 360 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 516 trials still running at the 2026-10-09 snapshot; registered median of 26 months across 3,198 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Arrhythmias, Cardiac trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 89
Phase 1/2 28
Phase 2 192
Phase 2/3 34
Phase 3 304
Phase 4 498
Not applicable 2,435
Observational 2,155
Expanded access 2
Unknown 2

How many Arrhythmias, Cardiac trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 323
Recruiting 729
Enrolling by invitation 67
Active, not recruiting 230
Available 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Arrhythmias, Cardiac trials? (10)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Abbott Medical Devices 123
Boston Scientific Corporation 118
Medtronic Cardiac Rhythm and Heart Failure 102
Bayer 59
Biosense Webster, Inc. 59

Which drugs are being tested for Arrhythmias, Cardiac? (8)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Rivaroxaban 91
Edoxaban 43
Dabigatran 42
DRONEDARONE 26
Flecainide 22

Interventions as named in the registry (7)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Warfarin VKA 88
Apixaban IR 67
amiodarone amiodarone 61
EC Aspirin 26
BIBR 1048 low1 25

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Arrhythmias, Cardiac trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 3,617 129
Atrial fibrillation 3,008 98
Cardiac failure 2,936 72
Myocardial Infarction (MI) 1,928 1
Hospitalization for ischemic or hemorrhagic stroke or systemic embolism or bleeding 1,497 1

Which publications cover Arrhythmias, Cardiac? (1,755)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (12)

MeSH descendants one level down with at least one trial, most trials first.

+2 more sub-conditions

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages