Condition (MeSH)
Yellow Fever
ClinicalTrials.gov lists 44 trials for Yellow Fever or a narrower condition beneath it. Sanofi Pasteur, a Sanofi Company has the most among industry and government lead sponsors, with 7.
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Trials per phase
44 of the 44 trials are tagged with Yellow Fever itself; the rest are tagged with a narrower condition beneath it.
When did Yellow Fever trials start? (19)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 5 |
| 2024 | 3 |
| 2023 | 3 |
| 2022 | 5 |
| 2021 | 4 |
| 2020 | 3 |
| 2019 | 2 |
| 2018 | 4 |
| 2017 | 2 |
Showing 10 of 19 earlier years.
No forecast is made for this condition: it averages 3.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Yellow Fever trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 6 |
| Phase 1/2 | 2 |
| Phase 2 | 8 |
| Phase 3 | 10 |
| Phase 4 | 5 |
| Not applicable | 7 |
| Observational | 6 |
How many Yellow Fever trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 4 |
| Active, not recruiting | 3 |
| Completed | 28 |
| Terminated | 1 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Yellow Fever trials? (9)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Sanofi Pasteur, a Sanofi Company | 7 |
| Sanofi | 3 |
| Serum Institute of India Pvt. Ltd. | 2 |
| ANRS, Emerging Infectious Diseases | 1 |
| AstriVax Therapeutics | 1 |
Showing 5 of 9 sponsors.
Which drugs are being tested for Yellow Fever? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Yellow Fever Vaccine | 22 |
| IC51 | 3 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Yellow fever vaccine, Institut Pasteur | 2 |
| Measles-Rubella vaccine (Live) I.P. (Freeze Dried) of M/s. Zydus Lifesciences Ltd | 1 |
| BLOOD SAMPLES | 1 |
| IMOJEV | 1 |
| AVX70481 low dose level | 1 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Yellow Fever trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pneumonia | 25 | 3 |
| Febrile convulsion | 10 | 1 |
| Urinary tract infection | 7 | 1 |
| Cellulitis | 4 | 2 |
| Covid-19 | 4 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Yellow Fever? (92)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Low-Dose Yellow Fever Vaccine in Adults in Africa. | The New England journal of medicine | 2025 | Yes |
| Immunogenicity of a single dose of the 17DD yellow fever vaccine in a cohort of adults and children in a non-endemic area, and its association with dengue and Zika seropositivity. | PLoS neglected tropical diseases | 2025 | Yes |
| Duration of post-vaccination immunity to yellow fever in volunteers ten years after a dose-response study - A complementary study. | Vaccine | 2024 | Yes |
| Next generation yellow fever vaccine induces an equivalent immune and transcriptomic profile to the current vaccine: observations from a phase I randomised clinical trial. | EBioMedicine | 2024 | Yes |
| Immunogenicity and safety of concomitant and sequential administration of yellow fever YF-17D vaccine and tetravalent dengue vaccine candidate TAK-003: A phase 3 randomized, controlled study. | PLoS neglected tropical diseases | 2023 | Yes |
Showing 5 of 92 publications.
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Yellow fever | Annual incidence | <1 / 1 000 000 | Europe | Not stated | Exact |
| Yellow fever | Point prevalence | Unknown | Worldwide | Not stated | Unspecified |
| Yellow fever | Annual incidence | <1 / 1 000 000 | Europe | Not stated | Exact |
| Yellow fever | Annual incidence | <1 / 1 000 000 | Europe | Not stated | Unspecified |
| Yellow fever | Point prevalence | Unknown | Worldwide | Not stated | Exact |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Yellow fever | 99829 | Exact | Orphadata Science knowledge files, Product 1 |
| Yellow fever | 99829 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.