Condition (MeSH)
Aniridia
ClinicalTrials.gov lists 23 trials for Aniridia or a narrower condition beneath it. National Eye Institute (NEI) has the most among industry and government lead sponsors, with 3.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
22 of the 23 trials are tagged with Aniridia itself; the rest are tagged with a narrower condition beneath it.
When did Aniridia trials start? (13)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Not applicable
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 1 |
| 2024 | 3 |
| 2023 | 4 |
| 2021 | 1 |
| 2018 | 1 |
| 2017 | 2 |
| 2016 | 1 |
| 2015 | 1 |
| 2010 | 2 |
| 2008 | 2 |
Showing 10 of 13 earlier years.
No forecast is made for this condition: it averages 1.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Aniridia trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 1/2 | 1 |
| Phase 2 | 2 |
| Not applicable | 6 |
| Observational | 13 |
How many Aniridia trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 7 |
| Completed | 13 |
| Withdrawn | 1 |
| Unknown status | 2 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Aniridia trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Eye Institute (NEI) | 3 |
| PTC Therapeutics | 2 |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1 |
| Fondation Ophtalmologique Adolphe de Rothschild | 1 |
| Implandata Ophthalmic Products GmbH | 1 |
Showing 5 of 6 sponsors.
Which drugs are being tested for Aniridia? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Ataluren | 2 |
Interventions as named in the registry (2)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| blood specimen | 1 |
| Blood Sampling | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Aniridia trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Retinal detachment | 3 | 2 |
| Corneal transplant | 2 | 1 |
| Cystoid macular oedema | 2 | 1 |
| Intraocular pressure increased | 2 | 1 |
| Mental disorder | 2 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Aniridia? (8)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Protein profiling of conjunctival impression cytology samples of aniridia subjects. | Acta ophthalmologica | 2024 | Yes |
| A novel de novo intronic variant in ITPR1 causes Gillespie syndrome. | American journal of medical genetics. Part A | 2021 | Yes |
| Outcomes of a modified capsular tension ring with a single black occluder paddle for eyes with congenital and acquired iris defects: Report 2. | Journal of cataract and refractive surgery | 2015 | Yes |
| Morcher iris reconstruction lens and rigid contact lens for traumatic aniridia. | Eye & contact lens | 2009 | Yes |
| Interim results of a compassionate-use clinical trial of Morcher iris diaphragm implantation: report 1. | Journal of cataract and refractive surgery | 2008 | Yes |
Showing 5 of 8 publications.
Sub-conditions in MeSH (1)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.