Condition (MeSH)
Meningitis, Cryptococcal
ClinicalTrials.gov lists 54 trials for Meningitis, Cryptococcal or a narrower condition beneath it. Pfizer has the most among industry and government lead sponsors, with 11.
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Trials per phase
54 of the 54 trials are tagged with Meningitis, Cryptococcal itself; the rest are tagged with a narrower condition beneath it.
When did Meningitis, Cryptococcal trials start? (20)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 1 |
| 2024 | 1 |
| 2023 | 3 |
| 2022 | 1 |
| 2021 | 1 |
| 2020 | 3 |
| 2019 | 2 |
| 2017 | 1 |
| 2016 | 2 |
| 2015 | 6 |
Showing 10 of 20 earlier years.
No forecast is made for this condition: it averages 1.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Meningitis, Cryptococcal trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 4 |
| Phase 1/2 | 2 |
| Phase 2 | 7 |
| Phase 2/3 | 3 |
| Phase 3 | 6 |
| Phase 4 | 5 |
| Not applicable | 19 |
| Observational | 8 |
How many Meningitis, Cryptococcal trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 4 |
| Enrolling by invitation | 1 |
| Completed | 35 |
| Terminated | 2 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Meningitis, Cryptococcal trials? (7)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Pfizer | 11 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 8 |
| National Hospital for Tropical Diseases, Hanoi, Vietnam | 3 |
| ANRS, Emerging Infectious Diseases | 2 |
| Matinas BioPharma Nanotechnologies, Inc. | 2 |
Showing 5 of 7 sponsors.
Which drugs are being tested for Meningitis, Cryptococcal? (5)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| AMPHOTERICIN B | 18 |
| Flucytosine | 11 |
| Itraconazole | 2 |
| Amphotericin B Deoxycholate | 2 |
| Efungumab (Mycograb) | 2 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Fluconazol | 25 |
| liposomal Amphotericine B | 2 |
| MAT2203 | 2 |
| Oteseconazole with Flucytosine - antifungal therapy 4 | 1 |
| 10-Week Fluconazole | 1 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Meningitis, Cryptococcal trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Anemia | 110 | 2 |
| Grade 4 Serious AEs | 80 | 1 |
| Grade 3 Serious AEs | 78 | 1 |
| Hyponatremia | 36 | 2 |
| Meningitis cryptococcal | 35 | 2 |
Showing 5 of 10 adverse events.
Which publications cover Meningitis, Cryptococcal? (77)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 77 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.