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Condition (MeSH)

AIDS-Related Opportunistic Infections

ClinicalTrials.gov lists 167 trials for AIDS-Related Opportunistic Infections or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 79.

MeSH D017088 Infections C01 C20
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Phase 1 Phase 1 21 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 23 Phase 3 Phase 3 23 Phase 4 Phase 4 2 Not applicable Not applicable 86 Observational Observational 11 Phase 1 Phase 1 21 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 23 Phase 3 Phase 3 23 Phase 4 Phase 4 2 Not applicable Not applicable 86 Observational Observational 11

Trials per phase (log scale)

167 of the 167 trials are tagged with AIDS-Related Opportunistic Infections itself; the rest are tagged with a narrower condition beneath it.

Get the AIDS-Related Opportunistic Infections report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did AIDS-Related Opportunistic Infections trials start? (11)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 2

1992: 1 trials (Observational 1) 1997: 1 trials (Not applicable 1) 1998: 1 trials (Phase 3 1) 2000: 2 trials (Observational 1, Phase 3 1) 2003: 1 trials (Phase 4 1) 2015: 1 trials (Observational 1) 2016: 1 trials (Not applicable 1) 2017: 1 trials (Phase 3 1) 2020: 1 trials (Not applicable 1) 2021: 1 trials (Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 2
2021 1
2020 1
2017 1
2016 1
2015 1
2003 1
2000 2
1998 1
1997 1

No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 167 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are AIDS-Related Opportunistic Infections trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 21
Phase 1/2 1
Phase 2 23
Phase 3 23
Phase 4 2
Not applicable 86
Observational 11

How many AIDS-Related Opportunistic Infections trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 2
Completed 152
Terminated 6
Withdrawn 4
Unknown status 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most AIDS-Related Opportunistic Infections trials? (15)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Institute of Allergy and Infectious Diseases (NIAID) 79
Pfizer 13
Hoffmann-La Roche 8
Astra USA 5
Fisons 5

Which drugs are being tested for AIDS-Related Opportunistic Infections? (8)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Zidovudine 18
Ganciclovir 16
Pentamidine Isethionate 16
Foscarnet 12
AMPHOTERICIN B 10

Interventions as named in the registry (7)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Fluconazol 21
Trimethoprim / Sulfamethoxazole 9
Isoniazida 8
Pyrazinamide Oral Product 6
Ethambutol Oral Product 5

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do AIDS-Related Opportunistic Infections trials report? (6)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Mania with Psychotic Disorder 2 1
Acute Gastrointestinal bleeding 1 1
Death 1 1
Meningitis 1 1
Psychosis with Serotonin Syndrome 1 1

Which publications cover AIDS-Related Opportunistic Infections? (671)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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